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Exhibitor Presentation
Renishaw Inc
2:30 pm - 4:00 pm, Room 513
Innovative Raman Imaging in the Life Sciences
When light illuminates a sample, most of it scatters without changing. A
tiny fraction of the light however is Raman scattered. The Raman scat-
tered light excites the phonons in the samples and produces a spectrum.
This spectrum tells us how the atoms are vibrating, providing a chemical
fingerprint which allows identification of the sample. Raman spectros-
copy produces chemical and structural information to help us under-
stand more about the material being analyzed. The ability to probe
the chemical and molecular structure of biological materials is obtained
directly without the need for any dyes or markers. These systems can be
utilized to generate chemical images of cells, tissue, bone and bio-com-
patible materials with very high spatial resolution. It has been employed
for cancer diagnosis, stem cell differentiation, skin treatments, protein
structure analysis, bio-diagnostics and bacterial identification.
Renishaw’s inVia confocal Raman microscope can be integrated with
other instruments, such as atomic force microscopy (AFM) and scanning
electron microscopy (SEM), to provide Raman analysis from the same
point on the sample. This talk will provide an introduction to Raman mi-
croscopy with biological materials, the instrumentation required for these
techniques and will highlight some applications where Raman microscopy
is making the biggest impact with biological materials
.
Speakers
Tim Prusnick, USA Sales Manager SPD, Renishaw Inc
Andrew King, Regional Sales Manager - West Coast, Renishaw Inc
Mark Canales, Field Applications Specialist (Life Science) Spectroscopy
Products Division, Renishaw Inc
Membership Committee Meeting
3:00 pm - 5:00 pm, Room 506
Exhibitor Presentation
Bruker Nano Surfaces
3:30 pm - 5:00 pm, Room 505
Advances in Live Super-Resolution Imaging Using the Vutara 352 Micro-
scope
Super-resolution microscopy has made a significant impact in the field
of biological imaging by enabling a ten-fold improvement in spatial reso-
lution over traditional light microscopy techniques. Most of the imaging
has been so far targeted at fixed specimens with a few live cell applica-
tions. The Vutara 352 microscope has been engineered towards live-cell
imaging by enhancing spatial and temporal resolution in single molecule
localization super-resolution. The sCMOS detector in the Vutara 352
enables imaging at 800 fps at full ROI and at video frame rates at reduced
ROI. Two color simultaneous imaging can be applied in both super-reso-
lution live cell and 3D particle tracking experiments. The biplane based
detection path enables imaging thicker samples such as whole mount
Drosophila and offers deeper penetration into tissues. The Vutara 352
also includes real time localization along with several statistical and live
cell analysis features for processing data. In summary, the Vutara 352
microscope is a powerful super-resolution imaging and analysis tool.
Speaker
Manasa Gudheti, Applications Scientist at Bruker – Fluorescence Micro-
copy Business
Career Center Workshop
Successfully Navigating the International Job
Search
4:00 pm - 5:00 pm, Room 518
Applying for a job in one country while finishing up your education and
training in another can be challenging, but it can be done with success. In
this workshop we will discuss specific strategies to finding jobs in another
country while one is abroad and how to leverage your networks in-
country to access opportunities, especially those that are hidden. Special
emphasis will be placed on establishing your reputation as a leader in
your field with professionals in the country or region in which you wish to
work. Case studies will be shared.
Symposium
Molecular Mechanisms of Mechanosensation
4:00 pm - 6:00 pm, Petree Hall C
Chair
Robert Fettiplace, University of Wisconsin-Madison
975-Symp
4:00 pm
GLOBAL AND SPECIFIC INTERACTIONS BETWEEN MECHANOSENSITIVE
ION CHANNELS AND THE LIPID BILAYER.
Boris Martinac
976-Symp
4:30 pm
SINGLE MOLECULE FORCE SPECTROSCOPY OF HAIR-CELL TIP-LINK PRO-
TEINS. Mounir A. Koussa, AndrewWard, Marcos Sotomayor, Wesley P.
Wong,
David P. Corey
977-Symp
5:00 pm
LOCALIZATION OF ANOMALOUS MECHANO-SENSITIVE ION CHANNELS IN
COCHLEAR HAIR CELLS. Maryline Beurg, Adam Goldring,
Robert Fettiplace
No Abstract
5:30 pm
STRUCTURE AND CHEMICAL BIOLOGY OF MECHANOSENSITIVE K2P
CHANNELS.
Daniel L. Minor
Symposium
Folding Rates and Routes
4:00 pm - 6:00 pm, Petree Hall D
Chair
Jane Clarke, University of Cambridge, United Kingdom
978-Symp
4:00 pm
ASSESSING AND MANIPULATING PROTEIN FOLDING DYNAMICS.
Feng Gai
No Abstract
4:30 pm
COUPLED PROTEIN FOLDING AND BINDING REACTIONS: MECHANISMS
AND SPEED LIMITS.
Thomas Kiefhaber
979-Symp
5:00 pm
IMPACTS OF CHARGE PATTERNING ON INTRINSICALLY DISORDERED
PROTEINS AND MECHANISMS OF DISORDER-TO-ORDER TRANSITIONS.
Rohit V. Pappu
980-Symp
5:30 pm
THE ROLE OF DISORDER IN PROTEIN FOLDING.
Jane Clarke