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932-Plat
12:00 pm
DELETION OF CYTOPLASMIC GATING RING ALTERS VOLTAGE DEPENDENT
ACTIVATION OF BK CHANNELS.
Guohui Zhang
, Yanyan Geng, Jingyi Shi,
Kelli McFarland, Karl L. Magleby, Lawrence Salkoff, Jianmin Cui
933-Plat
12:15 pm
SELECTIVE CATION BINDING TO THE GATING-RING TRIGGERS INDE-
PENDENT RCK MOTIONS IN THE BK CHANNEL.
Pablo Miranda
, Teresa
Giraldez, Miguel Holmgren
934-Plat
12:30 pm
ROLE OF AN INTERSUBUNIT CA
2+
BRIDGE IN STRUCTURE AND FUNC-
TION OF BK CHANNELS.
Alexandre G. Vouga
, Eunan Hendron, Brad S.
Rothberg
Platform
Computational Methods and Bioinformatics
10:45 am - 12:45 pm, Room 502B
Co-Chairs
Lanyuan Lu, Nanyang Technological University, Singapore
Liskin Swint-Kruse, University of Kansas
935-Plat
10:45 am
PL-PATCHSURFER: A FAST, SURFACE-PATCH-BASED VIRTUAL SCREENING
PROGRAM USING THREE-DIMENSIONAL ZERNIKE DESCRIPTORS.
Woong-Hee Shin
, Daisuke Kihara
936-Plat
11:00 am
BIASING THE SAMPLING OF LOCAL STATES TO DRIVE THE EXPLORA-
TION OF GLOBAL CONFORMATIONS IN PROTEINS.
Alessandro Pandini
,
Arianna Fornili
937-Plat
11:15 am
PROTEIN STRUCTURE DETERMINATION BY CONFORMATIONAL SPACE AN-
NEALING USING NMR GEOMETRIC RESTRAINTS.
Jooyoung Lee
,
Keehyoung Joo, InSuk Joung, Jinhyuk Lee, Jinwoo Lee, Weontae Lee,
Bernard Brooks, Sung Jong Lee
938-Plat
11:30 am
MODELING SOLUTION X-RAY SCATTERING WITH KNOWLEDGE-BASED
COARSE-GRAINED FORM FACTORS.
Lanyuan Lu
, Dudu Tong
939-Plat
11:45 am
DECODING DYNAMIC DISORDER IN SINGLE MOLECULE DATA.
Wonseok
Hwang
, Il-Buem Lee, Seok-Cheol Hong, Changbong Hyeon
940-Plat
12:00 pm
A NEW PATTERN IN PROTEIN EVOLUTIONARY SEQUENCE INFORMATION
ROBUSTLY IDENTIFIES FUNCTIONALLY-IMPORTANT AMINO ACID POSI-
TIONS.
Liskin Swint-Kruse
941-Plat
12:15 pm
AUTOMATED IMAGE ANALYSIS REVEALS SPATIALLY-REGULATED CELL DIVI-
SION DYNAMICS DURING DROSOPHILA AXIS ELONGATION.
Michael F.Z.
Wang
, Rodrigo Fernandez-Gonzalez
942-Plat
12:30 pm
AGENT-BASED MODELING OF BIOLOGICAL PATHWAYS - A CASE-STUDY
ON MRNA EXPORT AND QUALITY CONTROL MECHANISM.
Mohammad
Soheilypour
, Mohammad Mofrad
Platform
Membrane Physical Chemistry II
10:45 am - 12:45 pm, Room 515A
Co-Chairs
Susanne Fenz, Wuerzburg University, Germany
Tommy Nylander, Lund University, Sweden
943-Plat
10:45 am
NANOPARTICLES INTERACTING WITH MEMBRANES: FROM ENGULFMENT
PATTERNS TO ENDOCYTOSIS.
Jaime Agudo-Canalejo
, Reinhard Lipowsky
944-Plat
11:00 am
ON THE FORMATION OF LIPID NANO-SCALE STRUCTURES AT INTERFACES
BEYOND PLANAR BILAYERS. Aleksandra Dabkowska, Cassandra Niman,
Gaelle Offranc Piret, Henrik Persson, Hanna Wacklin, Heiner Linke,
Christelle Prinz,
Tommy Nylander
945-Plat
11:15 am
α-SYNUCLEIN BOUND TO MITOCHONDRIAL MEMBRANES
⎯
CHANGES IN
LIPID BILAYER STRUCTURE AND MECHANICS.
Ana West
, Ben Brummel,
Jonathan Sachs
946-Plat
11:30 am
MEMBRANE FLUCTUATIONS EFFECT PROTEIN DIFFUSION AND INDUCE
PROTEIN AGGREGATION.
Kayla Sapp
, Lutz Maibaum
947-Plat
11:45 am
MEMBRANE PROTEIN CROWDING AT THE MESOSCALE: INSIGHTS FROM
MD SIMULATIONS.
Matthieu G. Chavent
, Anna Duncan, Jean Helie,
Patrice Rassam, Tyler Reddy, Joseph Goose, Colin Kleanthous, Mark S P
Sansom
948-Plat
12:00 pm
MEMBRANE MEDIATED COOPERATIVITY FACILITATES CADHERIN
CLUSTERING IN MODEL MEMBRANES.
Susanne Fenz
, Timo Bihr, Daniel
Schmidt, Rudolf Merkel, Kheya Sengupta, Udo Seifert, Ana-Suncana Smith
949-Plat
12:15 pm
MEMBRANE HETEROGENEITY AND ITS ROLE IN IMMUNE SIGNALING ELU-
CIDATED BY SPECTRAL IMAGING.
Erdinc Sezgin
, Christian Eggeling
950-Plat
12:30 pm
IONIZATION OF PHOSPHATIDYLINOSITOL (3,4,5)-TRISPHOSPHATE IN
MIXED LIPID MEMBRANES.
Joseph Thomas
, Zachary Graber, Emily
Johnson, Arne Gericke, Edgar E. Kooijman
Platform
Membrane Protein Structure and Folding II
10:45 am - 12:45 pm, Room 515B
Co-Chairs
Timothy Cross, Florida State University
Janice Robertson, University of Iowa
951-Plat
10:45 am
MEASURING REVERSIBLE CLC-EC1 DIMERIZATION IN MEMBRANES BY
SINGLE MOLECULE PHOTOBLEACHING.
Rahul Chadda
, Larry Friedman,
Mike Rigney, Luci-Kolmakova Partensky, Jeff Gelles, Janice L. Robertson
952-Plat
11:00 am
MAPPING THE ENERGY LANDSCAPE FOR SECOND STAGE FOLDING OF A
SINGLE MEMBRANE PROTEIN.
Duyoung Min
, Robert E. Jefferson, James
U. Bowie, Tae-Young Yoon
953-Plat
11:15 am
SYNCHROTRON RADIATION CIRCULAR DICHROISM (SRCD) SPECTROSCO-
PY INVESTIGATIONS OF THE STRUCTURE AND ORIENTATION OF MEM-
BRANE PROTEINS IN ORIENTED LIPID BILAYERS.
Luke S. Evans
, Rohanah
Hussain, Giuliano Siligardi, Philip T. F. Williamson
954-Plat
11:30 am
MECHANISMS OF ASSEMBLY AND COVALENT FLAVINYLATION IN COM-
PLEX II.
Chrystal Starbird
, Elena Maklashina, Sany Rajagukguk, Gary
Cecchini, Tina Iverson