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Fitzpatrick, P.F., Orville, A.M., Nagpal, A., and Valley, M.P. “Nitroalkane oxidase, a carbanion-forming
flavoprotein homologous to acyl-CoA dehydrogenase.”
Arch.Biochem.Biophys.
(2005)
433:
157-65.
Nagpal, A., Valley, M.P., Fitzpatrick, P.F., and Orville, A.M. “Crystallization and preliminary analysis of active
nitroalkane oxidase in three crystal forms.”
Acta.Crystallogr.D.Biol.Crystallogr.
(2004)
60:
1456-60.
Valley, M.P. and Fitzpatrick, P.F. “Comparison of Enzymatic and Non-Enzymatic Nitroethane Anion
Formation: Thermodynamics and Contribution of Tunneling.”
J.Am.Chem.Soc.
(2004)
126
:6244-6245
.
Valley, M.P. and Fitzpatrick, P.F. “Reductive Half-Reaction of Nitroalkane Oxidase: Effect of Mutation of the
Active Site Aspartate to Glutamate.”
Biochemistry
(2003)
42
:5850-5856.
Valley, M.P. and Fitzpatrick, P.F. “Inactivation of Nitroalkane Oxidase upon Mutation of the Active Site Base
and Rescue with a Deprotonated Substrate.”
J.Am.Chem.Soc.
(2003)
125
:8738-8739.
Daubner, S.C., Gadda, G., Valley, M.P., and Fitzpatrick, P.F. “Cloning of Nitroalkane Oxidase from
Fusarium
oxysporum
Identifies a New Member of the Acyl-CoA Dehydrogenase Superfamily.”
Proc.Natl.Acad.Sci.U.S.A.
(2002)
99
:2702-2707.
Valley, M.P., Burk, D., Frazee, R.W., Yu, H., Dolbeare, K.B., Ohlendorf, D.H., and Lipscomb, J.D.
“Differences in Single versus Multiple Turnover of a Mutant Protocatechuate 3,4-Dioxygenase: A Short Circuit
in Catalysis.”
In preparation.
Vetting, M.W., Valley, M.P., D’Argenio, D., Ornston, L.N., Lipscomb, J.D., and Ohlendorf, D.H. “Biophysical
Analysis of R457S and R133H Mutants of Protocatechuate 3,4-Dioxygenase from
Acinetobacter
Strain ADP1.”
In preparation.
Abstracts
Valley, M.P., Sobol, M., Karassina, N., Duellman, S., Leippe, D., and Vidugiriene, J. “New Bioluminescent
Assays Enable Easy Measurement of Glucose-Dependent Metabolic Pathways” Fifth Annual SLAS
Conference, San Diego, CA. January 23-27, 2016.
Valley, M.P., Sobol, M., Karassina, N., Duellman, S., Leippe, D., Aoyoma, N., Hancock, M., Carlson, C., and
Vidugiriene, J. “Sensitive and Easy to Use Bioluminescent Assays for Measuring Glucose Dependent Metabolic
Pathways” 75
th
Scientific Sessions, Boston, MA. June 5-9, 2015.
Valley, M.P., Sobol, M., Karassina, N., Duellman, S., Cali, J.J., and Vidugiriene, J. “A Bioluminescent Assay
for Measuring Glucose Uptake” AACR Annual Meeting 2015, Philadelphia, PA. April 18-22, 2015.
Valley, M.P., Kupcho, K.R., Zimprich, C.A., Leippe, D., Niles, A.L., Vidugiriene, J., Cali, J.J., Kelm, J.M.,
Moritz, W., and Lazar, D.F. “Luminescent Cell Health Assays for Tumor Spheroid Evaluation” AACR Annual
Meeting 2014, San Diego, CA. April 5-9, 2014.
Cali, J.J., Valley, M.P., Unch, J., Meisenheimer, P.L., and Lazar, D.F. “A Novel Cell Based ATP Assay with
Enhanced Operational Stability and Ease of Use” Third Annual SLAS Conference, San Diego, CA. January 18-
22, 2014.
Riss, T.L., Valley, M.P., Zimprich, C.A., Niles, A.L., Kupcho, K.R., and Lazar, D.F. “Design and Validation of
Bioluminescent Assays for 3D Cell Culture Models” Third Annual SLAS Conference, San Diego, CA. January
18-22, 2014.
Valley, M.P., Zimprich, C., Cali, J.J., and Lazar, D.F. “A Bioluminescent Cell Viability Assay Optimized for
3D Microtissues” AACR Annual Meeting 2013, Washington D.C. April 6-10, 2013.
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