1074 / 1224
absorbed
dose (Gy)
d
abs
-
D
d
+
D
d
d
abs
+
d
abs
-
equieffective dose
dose (Gy EQD2)
d
EQD2
d
EQD2
+
d
EQD2
-
d
abs
……… prescribed dose (Gy)
d
EQD2
……. d
abs
converted to (Gy EQD2)
D
d ……. … e.g. 30% d
abs
(Gy)
d
abs
-/+
……. prescribed dose –/+
D
d (Gy) = delivered dose in Gy
d
EQD2
-/+
…… d
abs
-/+
converted to Gy EQD2
d
abs
- d
abs
-
= d
abs
+
- d
abs
d
EQD2
– d
EQD2
-
< d
EQD2
+
– d
EQD2
e.g. n~500 with same prescribed dose and SD 30% / fx:
mean of delivered doses <d
EQD2
> from 500 patients > prescribed dose in EQD2
dose/fx
<d
EQD2
>
Translating random uncertainties to EQD2: