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Elements and interactions of the tumor secretome
Paltridge et al., BBA, 1834, 2233ff, 2013
in vitro - cellular level:
Supernatants
Co-culturing of multiple cell types
in vivo - tumor models:
Tumor interstitial fluid
Pleural effusion
Blood serum
patients – clinical level:
Tumor interstitial fluid
Pleural effusion
Blood serum
Clinical Lung Cancer Secretome Studies:
Biomarkers studies in serum and pleural effusion