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Immun-modulatory

factors

(IL-2,6, IFN

b

, etc

)

Vasculature- and

hypoxia-modulatory

factors

(VEGF, PLGF,

Osteopontin etc.

ECM- and

dissemination-

modulatory factors

(

TIMPs, LOX, PAI-1, etc

)

Growth- and

resistance-

modulatory factors

(

EGF, IGF, etc

)

Tumor Secretome and Radiation Resistance

Identification of Biomarkers for Relevant Processes (basal, under treatment)