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ADAM17 (A Disintegrin and Metalloprotease 17)
- Signaling Scissors
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=370
ADAM 17 also called TACE (tumor necrosis factor-α-converting enzyme)
Present at the trans-Golgi-network and plasma membrane
ADAM17 is overexpressed in NSCLC and correlates with poor patient survival
Tumour Biol. 2013 Jun;34(3):1813-8.