882 / 1851
Elderly with poor KPS: TMZ alone is an option
(ANOCEF study)
TMZ alone has an acceptable tolerance in elderly GBM patients with low KPS (<70) and increases
survival compared with supportive care alone, especially in those with methylated MGMT promoter
Median PFS:
26 vs 11 months
Median OS:
31 vs 19 months
p = 0.03
p = 0.03
Perez-Larraya JG. et al. JCO 2011;29