883 / 1851
Perry JR et al, NEJM 2017;376
Newly diagnosed Glioblastoma
Patients 65 years of age or older
(median age 73)
RT dose: 40 Gy/15 fractions
Concurrent TMZ: 75 mg/m
2
/day for
21 consecutive days
Adjuvant TMZ: 150-200 mg/m
2
/day for
5 consecutive days out of 28 for up to
12 cycles or until progression
TMZ + “short-course” RT in Elderly: New standard regimen ?