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RCT (
R
andomised
C
ontrolled
T
rial)
True if main purpose is to
improve efficacy
(local control and survival)
Reduction of radiation-induced side effects?
Randomisation
Standard technique
e.g. IMRT (photons)
New technology
e.g. IMPT (protons)
Courtesy of Hans Langendijk, UMC Groningen
Evidence-based medicine: gold standard