Author
Patients (n)
Results
Grabenbauer
38
CD3/CD4: decreased 3 years NED
Rubio
277
CD3/CD8: increased 15 years survival
intratumoral CD8: increased DFS
Prognostic relevance of TILs
Hu
40
peritumoral CD8: increased OS
Gilbert
153
increased relapse-free survival
Grabenbauer G, Clin Cancer Res 2006; Rubio C, Int J Clin Exp Pathol 2008; Hu W, J Surg Oncol. 2015; Gilbert DC, Br J Cancer 2016
High levels of TILs, especially CD8(+) cells, are associated
with a favourable clinical response and survival