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Author

Patients (n)

Results

Grabenbauer

38

CD3/CD4: decreased 3 years NED

Rubio

277

CD3/CD8: increased 15 years survival

intratumoral CD8: increased DFS

Prognostic relevance of TILs

Hu

40

peritumoral CD8: increased OS

Gilbert

153

increased relapse-free survival

Grabenbauer G, Clin Cancer Res 2006; Rubio C, Int J Clin Exp Pathol 2008; Hu W, J Surg Oncol. 2015; Gilbert DC, Br J Cancer 2016

High levels of TILs, especially CD8(+) cells, are associated

with a favourable clinical response and survival