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Marker

No. of

patients

CD8(+)

low

CD8(+)

high

p-value

HPV-16 load

HPV-16 ≤ Med

39

24 (61.6%)

15 (37.5%)

0.033

Correlation CD8(+) TILs and HPV16/p16

INK4a

HPV-16 > Med

40

15 (38.4)

25 (62.5)

p16

INK4a

p16 WS ≤ 6

p16 WS > 6

23

71

16 (33.3%)

32 (66.7%)

32 (45.0%)

39 (55.0%)

0.042