Microsoft Word - 0_Florence_Masterclass_2017

Is there a future for planning studies to compare

treatment techniques?

Planning studies are essential:

- often clinical studies not feasible

- get a fast answer regarding difference in plan quality,

delivery time, MUs, ..

- can be hypothesis generating for clinical studies

- patient selection: protons vs. photons

Need to be done well:

- avoid bias

- enough patients

- clinically deliverable plans

- plans have to be checked by clinicians

Automated planning can help

Bias-free treatment technique comparison



exactly the same optimization algorithm/scheme



exactly the same planning constraints and

prioritized treatment objectives (‘wish-list’)