1374-1375 / 2605
NIRS: trial methodology
• Evidence-based choice of schedule
– Radiotherapy only
– Radio-systemic therapy
– Pre/post-operative radio(systemic)therapy
• Educated guess of start schedule
– Systemic therapy schedule
– CIRT dose and fractionation
• Systemic therapy is optimized first
Kamada T, et al. Lancet Oncol. 2015 Feb;16(2):e93-e100