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Trial outcome LA-PC NIRS

• Chemo(radio)therapy elsewhere

– Median survival: 8.5-13 months

– Severe toxicity: 30-50% G4-5

• C-ion+gemcitabine (NIRS high-dose)

– Median survival: >24 months

– Severe toxicity: 3/26 pts G4

• Concurrent gemcitabine at 1,000 mg/m2

Kamada T, et al. Lancet Oncol. 2015 Feb;16(2):e93-e100