ESTRO Brachytherapy for Prostate Cancer 2018

Even short time ADT can:

negatively impact QOL

increase morbidity

increase mortality

Evidence shown in observational studies

This is however NOT confirmed in RCTs

(? inclusion of older, more frail patients – reports on non-fatal events?)

Voog et al Eur Urolo 2016;69:204-210

Sanda et al N Eng J Med 2008; 358:1250-1261

Beyer D et al Int J Radiat Oncol Biol Phys 2005; 61:1299-1305