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Purpose: to

quantify

our concept of

quality

of a dose distribution

By convention: if

D

1

is

better

than

D

2

, then

F(D

1

) < F(D

2

)

:

search the

minimum

of

F

.

Commonly, the cost function has the form:

N

1

Properties of Cost Functions

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-48-

) (

Df

N

D

i

Dose in volume element

i

of an organ/tumour

Number of volume elements

number of

regret

assigned to the dose

D

in this volume

element

=

=

i

i

Df

N

F

1

) (