IMRT Course 2016

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Local Control of a Quadratic Overdose Penalty

red

/

yellow

voxels:

highest contribution to

the cost fuction (CF) ,

i.e. in these voxels the

CF puts most ‘pressure’

to the optimizer to

reduce dose

example:

quadratic overdose

penalty for D

0

=25Gy,

i.e. area of control

only at doses > 25 Gy

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-52-

25 Gy

Dummy

volume around

target for gradient