IMRT Course 2016

1648-1649 / 2953

) ( ) (
1
0
1
2
0 i
N
i
i underdose
DD DD
N
F − − = ∑
=
θ
) ( ) (
1
0
1
2
0
DD DD
N
F
i
N
i
i overdose
− − = ∑
=
θ
The most Common Physical Cost Function:
One-Sided Quadratic Penalties
ESTRO IMRT course 2016
IMRT optimization: algorithms&cost functions
London April 4th, 2016
-50-
Dose
Regret
The regret
grows quadratically
with the violation
of the required/
tolerated dose
D0