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Application:

target hot and cold

spots,

OARs with maximum

dose restrictions.

Limitations:

Cannot enforce a

Volume

-

-

-

-

+

+

Can quadratic penalties control

all aspects of dose?

ESTRO IMRT course 2016

IMRT optimization: algorithms&cost functions

London April 4th, 2016

-55-

?

strict dose limit.

Dose

-

-

-

-

++

+

-

-

-

-

-

-

-

-

-

Does not express

organ specific volume

effects.

Cannot be applied to

organs with a large

volume effect.