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Hypofractionation
•
Hypofractionation: delivery of larger doses of
radiation (>2 Gy) per fraction to reduce the overall
length of treatment
1
•
A lower alpha/beta ratio* in prostate cancer means
that a larger dose of radiation per treatment may
40
40
1. Ritter M, et al. Cancer J 2009;15(1):1–6
2. Aneja S et al. Oncology: Perspectives on Best Practices 2012; 6:1-9
provide improved efficacy in terms of tumour
control
1,2
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Advantages include reduced health care costs and
improved patient convenience
2
* Measure of a tissue’s predicted response to a radiation dose, relative to the size of the dose delivered per fraction