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Treatment of targets with large interfractional

deformations: Plan-selection strategies

Bondar et al. 2011 (Rad. Onc. 99(2)); courtesy M. Hoogeman (Erasmus MC)

ART for cervical cancer: For 90% of pts. with CTV coverage of >=95%…

Example:

female pelvis

ESTRO IMRT course 2016

Adaptive Radiotherapy

London April 7th, 2016

-41-

ART for bladder cancer, online adaptive 3-plan library:

compared to non-ART,

V

57Gy

of body tissue reduced by 34%

(Vestergaard et al. 2013, Rad. Onc. 109(3))

and

median PTV volume reduction by 30%

(Vestergaard et al. 2014, Acta Oncol. 53(8))

* non-ART population based

CTV-PTV volume 1702

±

274ml

(38mm margin)

* online-adaptive 2-plan library:

CTV-PTV volume 764

±

165ml

(7mm margin)

(Bondar et al. 2012, IJROBP 83(5))