IMRT Retrospective evidence: 2
165 IMRT vs 154 3D-CRT patients
Median time to local recurrence 18
months
5 year local recurrence rates:
IMRT
7.6%
3D-CRT 15.1%
p=0.05
Acute grade 2 skin reaction less
with lMRT (48.7% vs 31.5%)
Chronic ≥ grade 2 toxicity
(fractures, joint stiffness, oedema) no
difference
25
Folkert MR et al. Comparison of Local Recurrence With Conventional and Intensity-Modulated
Radiation Therapy for Primary Soft-Tissue Sarcomas of the Extremity. J Clin Oncol 2014, 32:3236-
3241