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IMRT Retrospective evidence: 2

165 IMRT vs 154 3D-CRT patients

Median time to local recurrence 18

months

5 year local recurrence rates:

IMRT

7.6%

3D-CRT 15.1%

p=0.05

Acute grade 2 skin reaction less

with lMRT (48.7% vs 31.5%)

Chronic ≥ grade 2 toxicity

(fractures, joint stiffness, oedema) no

difference

25

Folkert MR et al. Comparison of Local Recurrence With Conventional and Intensity-Modulated

Radiation Therapy for Primary Soft-Tissue Sarcomas of the Extremity. J Clin Oncol 2014, 32:3236-

3241