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• 41 patients
• WBRT of 20 RT of 40 Gy + boost Gy to
lesion (+ 2 cm margin)
• Overall median survival: 12 months
• <60 years: 23 months
• >60 years: 8 months
• KPS>70: 21 month
• KPS<70: 6 months
• Relapses inside and outside the “boost” area
RTOG 83-15 WBRT alone
Nelson DF et al: IJROBP 1992; 23:9-17