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• 41 patients

• WBRT of 20 RT of 40 Gy + boost Gy to

lesion (+ 2 cm margin)

• Overall median survival: 12 months

• <60 years: 23 months

• >60 years: 8 months

• KPS>70: 21 month

• KPS<70: 6 months

• Relapses inside and outside the “boost” area

RTOG 83-15 WBRT alone

Nelson DF et al: IJROBP 1992; 23:9-17