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Conclusions
• Large numbers of well conducted RCT supporting CMT
• Recent FDG-PET data inform patient specific discussions
about risk of relapse (increased over chemo alone)
versus late toxicity (potentially increased with CMT but
patient specific)
• Response adapted treatment using FDG PET
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Ongoing
challenges to implement in routine clinical practice with
QA measures required to meet Deauville criteria
• Patient specific risk models are being developed
alongside further biomarkers eg TMTV