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SWOG 7808 “low dose involved field radiation after
chemotherapy in advanced Hodgkin disease (1978-1988)
• Among 278 CR patients 5-year “similar” RFS was 79% vs
68% in favour of RT.
• P = 0.09 for the difference of 11%.
• RT improved relapse rate in
• patients with
nodular sclerosis
• 5-year relapse free 82% vs 60% (P = 0.002)
• Non-bulky NS: RFS 88% vs 68% favouring RT (P = 0.06)
• patients with
bulky disease
(>6cm)
• 5-year relapse free 75% vs 57% (P = 0.05).
Fabian C et al Ann Intern Med. 1994 Jun 1;120(11):903-12