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SWOG 7808 “low dose involved field radiation after

chemotherapy in advanced Hodgkin disease (1978-1988)

• Among 278 CR patients 5-year “similar” RFS was 79% vs

68% in favour of RT.

• P = 0.09 for the difference of 11%.

• RT improved relapse rate in

• patients with

nodular sclerosis

• 5-year relapse free 82% vs 60% (P = 0.002)

• Non-bulky NS: RFS 88% vs 68% favouring RT (P = 0.06)

• patients with

bulky disease

(>6cm)

• 5-year relapse free 75% vs 57% (P = 0.05).

Fabian C et al Ann Intern Med. 1994 Jun 1;120(11):903-12