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EORTC 20884 Conclusions

• No need for IFRT in patients who are in CR after

MOPP-ABV, only patients in PR after chemo benefit

• 45% of advanced stage patients who achieve “the

disappearance of all disease-related symptoms and

measurable lesions” do not require RT.

• Approximately 35% should receive RT based on

chemotherapy response (+ others who progress on

chemotherapy).

N Engl J Med. 2003 Jun 12;348(24):2396-406