EORTC 20884 Conclusions
• No need for IFRT in patients who are in CR after
MOPP-ABV, only patients in PR after chemo benefit
• 45% of advanced stage patients who achieve “the
disappearance of all disease-related symptoms and
measurable lesions” do not require RT.
• Approximately 35% should receive RT based on
chemotherapy response (+ others who progress on
chemotherapy).
N Engl J Med. 2003 Jun 12;348(24):2396-406