Slide 1

SWOG 7808 “low dose involved field radiation after

chemotherapy in advanced Hodgkin disease (1978-1988)

• 530 Stage III-IV patients enrolled.

• 322 achieved CR after MOP-BAP

• 278 pts randomized

• Randomized to low-dose RT (10-20 Gy) to all initially

involved sites vs observation.

• Abstract:

“Remission duration, relapse-free survival, and overall survival

were similar for the two groups (P = 0.09, P>0.2, and P = 0.14,

respectively).”

Fabian C et al Ann Intern Med. 1994 Jun 1;120(11):903-12