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Is radiotherapy curative for stage I and II low-grade follicular lymphoma?

Results of a long-term follow-up study of patients treated at Stanford University.

Mac Manus MP, Hoppe RT J Clin Oncol 1996 Apr;14(4):1282-90.

• 177 patients with stage I (n = 73 [41%]) and II (n = 104 [59%]) follicular

lymphoma Stanford University 1961 and 1994.

• RT either to one side of the diaphragm (IFRT or EFRT or to both sides

(total lymphoid irradiation [TLI] or subtotal lymphoid irradiation [STLI].

Doses 35 to 50 Gy.

• Median follow-up 7.7 years, longest 31 years. Median survival time

13.8 years.