148
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
2484-P
lat
8:30
am
FROM CHARGE STATE TO ISOSURFACES TO SPECTRA:
UNRAVELING THE MYSTERY OF LYS-TRP DIPEPTIDE
FLUORESCENCE.
Azaria Eisenberg
, Laura Juszczak
2485-P
lat
8:45
am
REAL-TIME QUANTIFICATION OF TIME-GATED
AUTOFLUORESCENCE SPECTRUM SHAPE TO TRACK
MITOCHONDRIAL METABOLISM.
Paul Urayama
, Jeff Maltas, Zac
Long, Arthur Oliva, Jeff Folz, Lana Amer, Dylan Palo
2486-P
lat
9:00
am
NANOSCALE INFRARED SPECTROSCOPY OF BIOLOGICAL
SYSTEMS.
Eoghan Dillon
, Mike Lo, Kevin Kjoller, Qichi Hu, Roshan
Shetty
2487-P
lat
9:15
am
FLAVONOLS AS LUMINESCENT PROBES OF WATER ACTIVITY
IN FOODS AND PHARMACEUTICALS. Siyu (Suzie) Wang, An N.
Le, Maria G. Corradini,
Richard D. Ludescher
2488-P
lat
9:30
am
SENSITIVE DETECTION OF NAD
+
/NADP
+
VIA STRONG
COUPLING FLUORESCENCE FROM SILVER NANOCLUSTERS.
Yufeng Yuan, Yan Chen, Kehan Huang, Haifeng Pan, Sanjun Zhang,
Jianhua Xu
2489-P
lat
9:45
am
NON-DESTRUCTIVE LABEL-FREE MONITORING OF DRUG
INTAKE IN LIVE CELLS USING ATR FT-IR SPECTROSCOPY.
Pedro L. Fale
, K. L. Andrew Chan
2490-P
lat
10:00
am
PHOTOBLEACHING CORRECTION IN FLUORESCENCE
CORRELATION SPECTROSCOPY.
Rudra P. Kafle
, Molly R.
Liebeskind, Jens-Christian Meiners
8:15
am
–10:15
am
, R
oom
307/308
Platform
Cell Mechanics, Mechanosensing, and
Motility II
Co-Chairs
Begona Alvarez-Gonzalez, University of California, San Diego
Christian Franck, Brown University
2491-P
lat
8:15
am
HIGH RESOLUTION, LARGE DEFORMATION 3D TRACTION
FORCE MICROSCOPY. Jennet Toyjanova, Eyal Bar-Kochba, Cristina
Lopez-Fagundo, Jonathan Reichner, Diane Hoffman-Kim,
Christian Franck
2492-P
lat
8:30
am
CORRELATIVE TRACTION FORCE MICROSCOPY AND
FLUORESCENCE FLUCTUATION ANALYSIS OF MOLECULAR
AGGREGATION AND COMPLEX FORMATION IN CELL
ADHESIONS IN DISTINCT MICROENVIRONMENTS.
Alexia I. Bachir
, Jessica Zareno, Kristopher E. Kubow, Sangyoon Han,
Kostadinos Moissoglu, Gaudenz Danuser, Enrico Gratton, Edward Plow,
Alan R. Horwitz
2493-P
lat
8:45
am
TRACKING ROTATION DURING LEUKOCYTE ROLLING
REVEALS ASYMMETRIC ADHESION PROPERTIES.
Isaac T.S. Li
,
Taekjip Ha, Yann R. Chemla
2494-P
lat
9:00
am
CHROMATIN ASSOCIATION WITH THE NUCLEAR ENVELOPE
SUPPORTS STABLE NUCLEAR MECHANICS.
Sarah M. Schreiner
,
Peter K. Koo, Yao Zhao, Simon G. J. Mochrie, Megan C. King
2495-P
lat
9:15
am
THREE-DIMENSIONAL BALANCE OF CORTICAL TENSION
AND AXIAL CONTRACTILITY ENABLES FAST AMOEBOID
MIGRATION.
Begona Alvarez-Gonzalez
, Ruedi Meili, Effie Bastounis,
Richard A. Firtel, Juan C. Lasheras, Juan C. del Alamo
2496-P
lat
9:30
am
MEASURING MECHANICAL FORCE DURING ZEBRAFISH
DEVELOPMENT USING AN EXPRESSIBLE TENSION SENSOR.
Andrea Hamilton
, Victoria Wu, Alex Dunn, Ingmar Riedel-Kruse
2497-P
lat
9:45
am
TWO DISTINCT REGIMES OF INTEGRIN MOLECULAR
FORCES.
Xuefeng Wang
, Taekjip Ha
2498-P
lat
10:00
am
DYNAMIC TRACTION FORCES OF HUMAN NEUTROPHIL
ADHESION.
Steven J. Henry
, Christopher S. Chen, John C. Crocker,
Daniel A. Hammer
8:15
am
–10:15
am
, R
oom
309/310
Platform
Intrinsically Disordered Proteins (IDP) and
Aggregates
Co-Chairs
Alexandra Klinger, University of Pennsylvania
Mark Brown, Yale University
2499-P
lat
8:15
am
SEQUENCE SPECIFIC RADIOLYTIC FOOTPRINTING STUDY
OF MONOMER, OLIGOMERIC AND FIBRILLAR AMYLOID
BETA (1-42).
Alexandra L. Klinger
, Janna Kiselar, Anant Paravastu,
Terrone Rosenberry
2500-P
lat
8:30
am
NOVEL METHODOLOGIES FOR THE COMPUTATIONAL
STUDY OF PROTEIN AGGREGATION.
David Shorthouse
, Thomas
Gallagher, Mark Sansom
2501-P
lat
8:45
am
MULTISCALE SIMULATIONS PROVIDE MECHANISTIC
INSIGHTS INTO THE EFFECTS OF SEQUENCE CONTEXTS ON
EARLY-STAGE POLYGLUTAMINE-MEDIATED AGGREGATION.
Kiersten M. Ruff
, Rohit V. Pappu
2502-P
lat
9:00
am
NEW INSIGHT INTO AMYLOID-
β
FIBRIL GROWTH AND ITS
INHIBITION: KINETIC NETWORK ANALYSIS OF MULTI-SCALE
MOLECULAR DYNAMICS SIMULATIONS.
Wei Han
, Klaus
Schulten
2503-P
lat
9:15
am
A ROLE FOR UNSTRUCTURED RESIDUES IN THE INDUCTION
OF MEMBRANE PORATION BY PRE-AMYLOID ASSEMBLIES
OF ISLET AMYLOID POLYPEPTIDE.
Mark A. Brown
, Elizabeth
Rhoades, Andrew D. Miranker
2504-P
lat
9:30
am
KEEPING IT DISORDERED: A NEW MECHANISM OF PROTEIN
QUALITY CONTROL?
Priya R. Banerjee
, Ashok Deniz