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150

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

1:00

pm

–3:00

pm

, B

allroom

III

Platform

Protein-Lipid Interactions III

Co-Chairs

Renee JiJi, University of Missouri

James Sturgis, Aix-Marseille Université, France

2523-P

lat

1:00

pm

ELUCIDATING THE INTERACTION OF 5-LIPOXYGENASE AND

FLAP.

Ramakrishnan B.Kumar

, Hans Hebert, Caroline Jegerschöld

2524-P

lat

1:15

pm

DESTABILIZING AQUAPORIN Z ASSEMBLY: EFFECTS ON

STRUCTURE, FUNCTION AND DYNAMICS. Victoria Schmidt,

Pierre Hubert, Valerie Prima,

James Sturgis

2525-P

lat

1:30

pm

THE ROLE OF LIPID ENVIRONMENT ON PEPTIDE

STRUCTURE AND FOLDING.

Renee D. JiJi

, Jian Xiong, Anahita

Zare, Jason W. Cooley

2526-P

lat

1:45

pm

INVESTIGATION ON THE INTERACTION BETWEEN PLEXIN

INTRACELLULAR PLUS TRANSMEMBRANE DOMAINS WITH

GTPASES AND WITH THE LIPID BILAYER USING ALL-ATOM

MOLECULAR DYNAMICS SIMULATIONS.

Liqun Zhang

, Buck

Matthias

2527-P

lat

2:00

pm

ROLE OF PHOSPHOLAMBAN MUTATIONS IN PROTEIN-

PROTEIN INTERACTIONS.

Vitaly V. Vostrikov

, Kailey J. Soller, Kim

N. Ha, Sarah E. Nelson, Tata Gopinath, Gianluigi Veglia

2528-P

lat

2:15

pm

SINGLE-MOLECULE FRET DETECTION OF GXXXG-MEDIATED

TRANSMEMBRANE HELIX-HELIX INTERACTIONS.

Yoshiaki Yano

, Kotaro Kondo, Katsumi Matsuzaki

2529-P

lat

2:30

pm

SPONTANEOUS RECONSTITUTION OF BOVINE RHODOPSIN

INTO ARTIFICIAL MEMBRANES.

Udeep Chawla

, Wan Zheng,

Liangju Kuang, Yunjiang Jiang, Suchithranga M. D. C. Perera, Michael F.

Brown, Hongjun Liang

2530-P

lat

2:45

pm

COARSE-GRAINED MODELING OF MINUTE-TIMESCALE CO-

TRANSLATIONAL MEMBRANE PROTEIN INTEGRATION VIA

THE SEC-TRANSLOCON.

Michiel J.M. Niesen

, Thomas F. Miller III

1:00

pm

–3:00

pm

, B

allroom

IV

Platform

Protein Folding and Chaperones

Co-Chairs

Wilfredo Colon, Rensselaer Polytechnic Institute

Liliana Quintanar, Cinvestav, Mexico

2531-P

lat

1:00

pm

PROTEOMICS-LEVEL IDENTIFICATION OF DEGRADATION-

RESISTANT PROTEINS PROVIDE INSIGHT ABOUT THEIR

POTENTIAL ROLES IN ORGANISMAL ADAPTATION TO

STRESS. Ke Xia, Jennifer Wilcox, Kayleigh Kobovitch, Brian Ortiz,

Areeg Khalil,

Wilfredo Colon

2532-P

lat

1:15

pm

international

travel awardee

SURPRISING ABUNDANCE OF MISFOLDING DURING

REFOLDING OF MULTIDOMAIN PROTEINS.

Alessandro Borgia

,

Katherine R. Kemplen, Madeleine B. Borgia, Robert B. Best, Andrea

Soranno, Daniel Nettels, Bengt Wunderlich, Jane Clarke, Benjamin

Schuler

2533-P

lat

1:30

pm

TWO-DIMENSIONAL FLUORESCENCE LIFETIME

CORRELATION SPECTROSCOPY ON THE FOLDING

MECHANISM OF B DOMAIN OF PROTEIN A.

Takuhiro Otosu

,

Kunihiko Ishii, Hiroyuki Oikawa, Munehito Arai, Satoshi Takahashi,

Tahei Tahara

2534-P

lat

1:45

pm

CONFORMATIONAL DYNAMICS OF MOLECULAR

CHAPERONES INVESTIGATED BY SINGLE MOLECULE

MULTICOLOR FÖRSTER RESONANCE ENERGY TRANSFER.

Lena Voith von Voithenberg

, Anders Barth, Swati Tyagi, Christine

Koehler, Edward A. Lemke, Don C. Lamb

2535-P

lat

2:00

pm

COPPER AND ZINC BINDING SPECIFICALLY INDUCE THE

AGGREGATION OF HUMAN

Γ

-D CRYSTALLIN.

Liliana Quintanar

, Evgene Serebryany, Jose Antonio Domínguez-Calva,

Cameron Haasse-Pettingell, Jonathan A. King

2536-P

lat

2:15

pm

education

travel awardee

ROLE OF PORE LOOPS IN THE MECHANISM OF POLYPEPTIDE

TRANSLOCATION BY A AAA+ PROTEASE MACHINE.

Piere Rodriguez-Aliaga

, Luis E. Ramirez, Frank Kim, Andreas Martin,

Carlos Bustamante

2537-P

lat

2:30

pm

(DIS)ASSEMBLY AND STRUCTURAL STABILITY OF MTHSP60

AND ITS PRECURSOR NAÏVE FORM.

Dario Spigolon

, Silvia Vilasi,

Maria Rosalia Mangione, PierLuigi San Biagio, Donatella Bulone

2538-P

lat

2:45

pm

CHARACTERIZING THE CONFORMATIONAL ENSEMBLES

OF THE E. COLI HSP70, DNAK REVEALS THE ROLE OF THE

INTERMEDIATE STATE.

Alex Liqi Lai

, Mandy Blackburn, Eugenia

M. Clerico, Peter Borbat, Lila M. Gierasch, Jack H. Freed

1:00

pm

–3:00

pm

, R

oom

307/308

Platform

Excitation-Contraction Coupling

Co-Chairs

Benjamin Prosser, University of Pennsylvania

William Louch, University of Oslo, Norway

2539-P

lat

1:00

pm

IDENTIFICATION OF A CALSEQUESTRIN-1 MUTATION

IN A HUMAN VACUOLAR MYOPATHY.

Daniela Rossi

, Bianca

Vezzani, Valeria Del Re, Virginia Barone, Simone Spinozzi, Alessandra

Gamberucci, Stefania Lorenzini, Cecilia Paolini, Feliciano Protasi, Carlo

Reggiani, Vincenzo Sorrentino, Lucia Galli

2540-P

lat

1:15

pm

MICROTUBULE DETYROSINATION MODULATES STRETCH-

DEPENDENT X-ROS SIGNALING IN HEART. Patrick G. Robison,

Jaclyn P. Kerr, Alexey I. Bogush, Daniel A. Harki, Christopher W. Ward,

Benjamin L. Prosser