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149

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

W

E

D

N

E

S

D

A

Y

2505-P

lat

9:45

am

HIV-TAT PROTEIN-AMYLOID BETA COMPLEX:

FROM MOLECULAR INTERACTION TO INCREASED

NEUROTOXICITY.

Alina Popescu Hategan

, Joseph Steiner, Mario A.

Bianchet, Elena Karnaukhova, Emilios K. Dimitriadis, Avindra Nath

2506-P

lat

10:00

am

THE INTRINSICALLY DISORDERED MEMBRANE ENZYMES

SELENOPROTEIN S AND SELENOPROTEIN K. Liu Jun, zhengqi

Zhang,

Sharon Rozovsky

8:15

am

–10:15

am

, R

oom

314/315

Platform

Membrane Active Peptides and Toxins

Co-Chairs

Patricia Clark, University of Notre Dame

B. Scott Perrin, NIH/NHLBI

2507-P

lat

8:15

am

MULTIPLE DRIVING FORCES CONTRIBUTE TO

TRANSLOCATION OF AUTOTRANSPORTER VIRULENCE

PROTEINS. Igor Drobnak, Esther Braselmann,

Patricia L. Clark

2508-P

lat

8:30

am

DECIPHERING PROTEIN MEMBRANE INTERACTIONS

INVOLVED IN THE TRANSLOCATION PROCESS OF A

BACTERIAL TOXIN, THE ADENYLATE CYCLASE (CYAA) TOXIN

FROM B. PERTUSSIS. Orso Subrini, Johanna Karst, Ana-Cristina

Sotomayor-Pérez, Audrey Hessel, Edithe Selwa, Nicolas Sapay, Rémi

Veneziano, Jonathan Pansieri, Joel Chopineau, Daniel Ladant,

Alexandre Chenal

2509-P

lat

8:45

am

MOVING ALONG THE FREE ENERGY LANDSCAPE OF

MEMBRANE INSERTION OF THE DIPHTHERIA TOXIN

TRANSLOCATION DOMAIN.

Mauricio Vargas-Uribe

, Mykola V.

Rodnin, Alexander Kyrychenko, Alexey S. Ladokhin

2510-P

lat

9:00

am

ASSESSING THE TRANSLOCATION OF CPPS USING FORCE

MEASUREMENT, SINGLE MOLECULES AND EMULSIONS.

Pierre Soule

, Abdou Rachid Thiam, Frédéric Pincet, Alain Joliot,

Sandrine Sagan, Sophie Cribier, Nicolas Rodriguez

2511-P

lat

9:15

am

SYNTHETIC MOLECULAR EVOLUTION APPROACH:

DISCOVERY AND CHARACTERIZATION OF NOVEL

ANTIVIRAL PEPTIDES.

Jing He

, Gregory Wiedman, Kalina Hristova,

William C. Wimley

2512-P

lat

9:30

am

PORE FORMATION MECHANISMS OF MELITTIN-LIKE

MEMBRANE-ACTIVE PEPTIDES.

Charles H. Chen

, Gregory

Wiedman, Yukun Wang, Ayesha Khan, Martin B. Ulmschneider

2513-P

lat

9:45

am

THE CURVATURE INDUCTION OF SURFACE-BOUND

ANTIMICROBIAL PEPTIDES PISCIDIN 1 AND PISCIDIN 3

VARIES WITH LIPID CHAIN LENGTH.

Bradley S. Perrin

,

Alexander J. Sodt, Myriam L. Cotten, Richard W. Pastor

2514-P

lat

10:00

am

A GENERAL MECHANISM FOR OFF-TARGET EFFECTS:

STUDIES WITH AMIODARONE AND OTHER

ANTIARRHYTHMICS.

Radda Rusinova

, Roger E. Koeppe II, Olaf S.

Andersen

9:00

am

–1:00

pm

, H

all

C

Biomolecular Discovery Dome

Visit this 3-D portable Dome, sponsored by the Public Affairs Committee,

to see how difficult biophysical topics can be made accessible to high

school students and the public. Short videos that communicate the

excitement of looking at macromolecular complexes and understanding

the molecular basis for life are being shown throughout the week.

10:30

am

–11:15

am

, H

all

C

Coffee Break

12:00

pm

–3:00

pm

, R

oom

333

Publications Committee Meeting

1:00

pm

–3:00

pm

, B

allroom

I

Symposium

Advances in Electron Microscopy

Chair

Yifan Cheng, University of California, San Francisco

2515-S

ymp

1:00

pm

CRYO-EM OF DNA REPAIR PROTEIN COMPLEXES.

Hong-Wei Wang

2516-S

ymp

1:30

pm

STRUCTURAL MATURATION OF HEPATITIS B CORE PROTEIN

CAPSIDS.

Bettina Boettcher

2517-S

ymp

2:00

pm

SINGLE PARTICLE CRYO-EM OF CALCIUM RELEASE

CHANNELS.

Irina I. Serysheva

2518-S

ymp

2:30

pm

SINGLE PARTICLE CRYOEM OF INTEGRAL MEMBRANE

PROTEINS.

Yifan Cheng

1:00

pm

–3:00

pm

, B

allroom

II

Symposium

Catalysis in the Membrane

Chair

Jochen Zimmer, University of Virginia

2519-S

ymp

1:00

pm

ZMPSTE24 AND PREMATURE AGEING: A UNIQUE INTEGRAL

MEMBRANE METALLOPROTEASE WITH A HOLE IN THE

MIDDLE.

Liz Carpenter

2520-S

ymp

1:30

pm

THE MECHANISM OF RHOMBOID INTRAMEMBRANE

PROTEASE.

Ya Ha

2521-S

ymp

2:00

pm

CLEAVAGE-DEPENDENT AND INDEPENDENT ROLE OF THE

SERINE PROTEASE CAP1/PRSS8.

Edith Hummler

2522-S

ymp

2:30

pm

A MOLECULAR DESCRIPTION OF CELLULOSE BIOSYNTHESIS.

Jochen Zimmer