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76

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

Protein Structure and Conformation II

(Boards B1-B28)

1050-P

os

B

oard

B1

STRUCTURAL RIGIDITY REGULATES FUNCTIONAL

INTERACTIONS IN THE HSP40-HSP70 MOLECULAR

MACHINE.

Neil Andrew D. Bascos

, Samuel J. Landry

1051-P

os

B

oard

B2

STRUCTURAL STUDIES OF SOLUBLE GUANYLATE

CYCLASE.

Kenneth Childers

, Franziska Seeger, Elsa Garcin

1052-P

os

B

oard

B3

GESTATION OF A GLU PLASMINOGEN SUPRA FOLD VIA

MOLECULAR DYNAMICS SIMULATION.

Hyunjin Kim

, Hyung J.

Kim, Miguel Llinas

1053-P

os

B

oard

B4

CONSTRAINED MAXIMUM LIKELIHOOD ESTIMATION

OF THE ABUNDANCES OF PROTEIN CONFORMATION

IN A HETEROGENEOUS STRUCTURAL ENSEMBLE

FROM SMALL ANGLE X-RAY SCATTERING INTENSITY

MEASUREMENTS.

Ahmet Emre Onuk

, Murat Akcakaya, Jaydeep

Bardhan, Deniz Erdogmus, Dana H. Brooks, Lee Makowski

1054-P

os

B

oard

B5

USING PHYSICS AND HEURISTICS IN PROTEIN STRUCTURE

PREDICTION.

Alberto Perez

, Justin MacCallum, Ken A. Dill

1055-P

os

B

oard

B6

ELUCIDATING THE FUNCTIONAL SIGNIFICANCE OF

THE C-TERMINAL HYPERVARIABLE REGION (HVR) IN

K-RAS4A.

Mayukh Chakrabarti

, Shaoyong Lu, Hyunbum Jang, Lyuba

Khavrutskii, Nadya I. Tarasova, Vadim Gaponenko, Ruth Nussinov

1056-P

os

B

oard

B7

THEORETICAL STUDY OF THE PROTEIN FOLDING

DYNAMICS FROM A TIME CORRELATION FUNCTION

APPROACH.

Toshifumi Mori

, Shinji Saito

1057-P

os

B

oard

B8

EXTENSIVE CONFORMATIONAL HETEROGENEITY WITHIN

PROTEIN CORES.

Gregory R. Bowman

1058-P

os

B

oard

B9

CONFORMATIONAL DYNAMICS OF THE PILI

CONSTRUCTING SORTASE C ENZYMES.

Emmanuel B. Naziga

,

Jeff Wereszczynski

1059-P

os

B

oard

B10

TARGETED CONFORMATIONAL TRANSITIONS OF

MULTIMERIC PROTEINS BY MONTE CARLO SIMULATIONS

COMBINED WITH COLLECTIVE ANISOTROPIC NETWORK

MODEL MODES. Yasemin Yesiltepe, Arzu Uyar, Deniz Turgut, Turkan

Haliloglu, Pemra Doruker,

Rahmi Ozisik

1060-P

os

B

oard

B11

CONFORMATIONAL FLUCTUATIONS AS AN INTRINSIC

MECHANISM OF ACTION OF LIPASE FOLDASE STUDIED

BY THE HIGH-PRECISION FRET TOOLKIT AND MD

SIMULATIONS.

Jakub Kubiak

, Filip Kovacic, Peter Dollinger, Florian

Bleffert, Karl-Erich Jaeger, Holger Gohlke, Claus A. M. Seidel

1061-P

os

B

oard

B12

NICKEL REDUCES CALCIUM-DEPENDANT DIMERIZATION BY

NEURAL CADHERIN.

Matthew P. Dukes

, Rhianon Kay Rowe, Susan

Pedigo

1062-P

os

B

oard

B13

EFFECTS OF R102Q MUTATION ON THE STRUCTURAL AND

DYNAMIC PROPERTIES OF HUMAN NEURONAL CALCIUM

SENSOR-1 PROTEIN.

Qingwen Zhang

, Yuzhen Zhu, Ying Wu,

Buyong Ma

1063-P

os

B

oard

B14

education

travel awardee

RNA TRANSLOCATION COUPLED TO LARGE-SCALE

CONFORMATIONAL TRANSITIONS OF A HEXAMERIC

HELICASE.

Wen Ma

, Klaus Schulten

1064-P

os

B

oard

B15

IDENTIFYING UNIQUE CONFORMATIONS IN THERMUS

THERMOPHILUS PHOSPHOFRUCTOKINASE USING

FLUORESCENCE PHASORS.

Xinxin Tian

, Mauricio Lasagna, Gregory

D. Reinhart

1065-P

os

B

oard

B16

PROBING PROTEIN INTERACTIONS OF CYANYLATED

ACYL CARRIER PROTEINS USING VIBRATIONAL

SPECTROSCOPY.

Connie Friedman

, Michael Jordan, Casey

Londergan, Louise Charkoudian

1066-P

os

B

oard

B17

IDENTIFICATION AND CHARACTERIZATION OF A YEAST

ISO-1-CYTOCHROME C C-TERMINAL DOMAIN SWAPPED

DIMER.

Levi J. McClelland

, Tung-Chung Mou, Stephen R. Sprang,

Bruce E. Bowler

1067-P

os

B

oard

B18

HEME COORDINATION VERSATILITY IN A TRUNCATED

HEMOGLOBIN.

Dillon Nye

, Matthew Preimesberger, Christos

Kougentakis, Selena Rice, Juliette Lecomte

1068-P

os

B

oard

B19

MODELING THE CALCIUM AND INTEGRIN BINDING

PROTEIN 2.

Olivia Dickens

, Raul Mendez-Giraldez, Nikolay

Dokholyan

1069-P

os

B

oard

B20

STRUCTURAL BEHAVIOR OF CARDIAC TROPONIN C

VARIANTS PRESENT IN CARDIOMYOPATHIC PATIENTS.

Mayra Marques

, José Pinto, Adolfo Moraes, Martha Sorenson, Jerson

Silva, Guilherme Oliveira

1070-P

os

B

oard

B21

METHIONINE-AROMATIC INTERACTIONS IN CALMODULIN:

A REPLICA EXCHANGE MD AND EPR SPECTROSCOPY

STUDY.

Tiffany L. Senkow

, Andrew K. Lewis, Megan R. McCarthy,

Cheng Her, David D. Thomas, Jonathan N. Sachs

1071-P

os

B

oard

B22

TARGETING MELANOMA WITH SMALL MOLECULES:

INHIBITORS OF THE CALCIUM-BINDING PROTEIN

S100B.

Michael C. Cavalier

, David J. Weber

1072-P

os

B

oard

B23

CRYSTALLIZATION STUDIES OF CALMODULIN BINDING

TARGETS.

Abigail L. Healy

, Jennifer Willemsen, Katrina Nayak, Janina

Sprenger, Roger Rowlett, Birgitta Frohm, Sara Linse, Karin Åkerfeldt

1073-P

os

B

oard

B24

TUNING OF STRUCTURE-FUNCTION RELATIONSHIPS BY

MACROMOLECULAR CROWDING.

Laurel Hoffman

, Xu Wang,

Hugo Sanabria, Margaret S. Cheung, John Putkey, Neal Waxham