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73

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

M

O

N

D

A

Y

1029-P

lat

5:00

pm

MAPPING LAC REPRESSOR INTERACTIONS ALONG DNA

WITH ULTRA-FAST OPTICAL TWEEZERS.

Alessia Tempestini

,

Carina Monico, Francesco Vanzi, Francesco Saverio Pavone, Marco

Capitanio

1030-P

lat

5:15

pm

DIRECT OBSERVATION OF TALE PROTEIN SEARCH

DYNAMICS ALONG DNA.

Luke W. Cuculis

, Zhanar Abil, Huimin

Zhao, Charles M. Schroeder

1031-P

lat

5:30

pm

DYNAMIC DNA TARGET PROOFREADING IN A CRISPR-CAS

SYSTEM.

Marius Rutkauskas

, Tomas Sinkunas, Maria S. Tikhomirova,

Virginijus Siksnys, Ralf Seidel

1032-P

lat

5:45

pm

SINGLE-MOLECULE IMAGING REVEALS DYNAMICS OF SA1-

TRF1 INTERACTIONS ON TELOMERIC DNA.

Jiangguo Lin

,

Haijiang Chen, Parminder Kaur, Wang Miao, Preston Countryman,

Changjiang You, Jacob Piehler, Yizhi J. Tao, Susan Smith, Hong Wang

4:00

pm

–6:00

pm

, R

oom

314/315

Platform

Molecular, Cellular, and Systems

Neuroscience: Experimental Approaches,

Modeling, and Tools

Co-Chairs

Jacob Robinson, Baylor College of Medicine

Benjamin Machta, Princeton University

1033-P

lat

4:00

pm

ELECTROPHYSIOLOGY-BASED SORTING AND SCREENING

WITH NANOWIRE ELECTRODES IN MICROFLUIDIC DEVICES.

Daniel L. Gonzales, Daniel G. Vercosa, Andrew M. Bell, Benjamin W.

Avants,

Jacob T. Robinson

1034-P

lat

4:15

pm

MECHANICAL SURFACE WAVES ACCOMPANY ACTION

POTENTIAL PROPAGATION.

Benjamin B. Machta

, Ahmed El Hady

1035-P

lat

4:30

pm

PENETRATION OF ACTION POTENTIALS DURING COLLISION

IN THE MEDIAL GIANT AXON OF INVERTEBRATES.

Rima Budvytyte

, Alfredo Gonzalez-Perez, Lars D. Mosgaard, Soren

Nissen, Thomas Heimburg

1036-P

lat

4:45

pm

DYNAMICS OF GLYCINE RECEPTORS AND THEIR

INTERACTIONS WITH GEPHYRIN SCAFFOLDS REVEALED

WITH HIGH-DENSITY SINGLE PARTICLE TRACKING AND

BAYESIAN INFERENCE.

Mohamed El Beheiry

, Jean-Baptiste Masson,

Charlotte Salvatico, Christian Specht, Antoine Triller, Maxime Dahan

1037-P

lat

5:00

pm

ROBUST OPTICAL STIMULATION OF NEURONAL ACTIVITY

USING FUNCTIONALIZED GOLD NANOPARTICLES.

João L. Carvalho-de-Souza

, Jeremy S. Treger, Bobo Dang, Stephen Kent,

David R. Pepperberg, Francisco Bezanilla

1038-P

lat

5:15

pm

LIGAND FINGERPRINTING IN THE MEMBRANE DYNAMICS

OF SINGLE TRKA AND P75NTR NEUROTROPHIN RECEPTORS.

Stefano Luin

, Laura Marchetti, Fulvio Bonsignore, Fabio Beltram,

Antonino Cattaneo

1039-P

lat

5:30

pm

LOCAL TEMPERATURE EVOLUTION DURING NANOPARTICLE

HYPERTHERMIA PROBED BY FLUORESCENCE

THERMOMETRY. Rahul Munshi, Idoia Castellanos-Rubio,

Arnd Pralle

1040-P

lat

5:45

pm

NANOMECHANICAL CHARACTERIZATION OF ACTIVE

SYNAPSES IN LIVE HIPPOCAMPAL NEURONS.

Ju Yang

, Roger

Lefort, Ozgur Sahin

4:00

pm

–6:00

pm

, R

oom

316/317

Platform

Large-scale Molecular Simulations

Co-Chairs

Juan Perilla, University of Illinois at Urbana-Champaign

Steven Poelzing, Virginia Tech

1041-P

lat

4:00

pm

COMPUTATIONAL STUDIES ON THE CAMP MODULATION OF

THE HCN2 CHANNEL.

Florentina Tofoleanu

, Bernard Brooks

1042-P

lat

4:15

pm

FROM SMALL TO LARGE TO VERY LARGE: MODELING OF

BIOMOLECULAR STRUCTURES IN IMPLICIT SOLVENT.

Alexey V. Onufriev

1043-P

lat

4:30

pm

ACUTE MODULATION OF SODIUM CHANNEL BIOPHYSICAL

PROPERTIES USING HIGH-FREQUENCY STIMULATION.

Steven Poelzing

, Michael Entz, Seth H. Weinberg

1044-P

lat

4:45

pm

ANALYSIS OF DOMAIN MOVEMENT AND DYNAMICS OF

NORWALK VIRUS CAPSID BY MOLECULAR DYNAMICS (ALL-

ATOM AND COARSE GRAINED) SIMULATIONS AND NORMAL

MODE ANALYSIS.

Mahendra B. Thapa

, Mark Rance, Jarek Meller

1045-P

lat

5:00

pm

STUDYING THE GATING MECHANISM OF MAMMALIAN KIR

CHANNELS USING IN SILICO MUTATIONS.

Eva-Maria Zangerl

,

Anna Stary-Weinzinger

1046-P

lat

5:15

pm

MULTISCALE ANALYSIS OF FUNCTIONAL MOTIONS IN F1-

ATPASE: FROM PI RELEASE TO ELASTICITY AND FRICTION OF

Γ

-SUBUNIT ROTATION.

Kei-ichi Okazaki

, Gerhard Hummer

1047-P

lat

5:30

pm

ION CHANNEL REGULATION BY LIPID BILAYERS: THEORY

& SIMULATION OF DEFORMED MEMBRANES AROUND

GRAMICIDIN A.

Andrew H. Beaven

, Alexander J. Sodt, Olaf S.

Andersen, Richard W. Pastor, Wonpil Im

1048-P

lat

5:45

pm

ATOMISTIC CHARACTERIZATION OF THE HIV CAPSID FROM

MOLECULAR DYNAMICS SIMULATIONS.

Juan R. Perilla

,

Klaus Schulten