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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
4:00
pm
–6:00
pm
, B
allroom
IV
Platform
Protein Lipid Interactions II
Co-Chairs
Sandro Keller, University of Kaiserslautern, Germany
Sarah McDonald, Johns Hopkins University
1009-P
lat
4:00
pm
AN UNUSUAL MEMBRANE-PROTEIN TOPOLOGY FOR
SENSING BILAYER THICKNESS AND TRIGGERING BACTERIAL
BIOFILM FORMATION.
Sandro Keller
, Jana Broecker, Sebastian
Fiedler, Katharina Gimpl, Martin Textor
1010-P
lat
4:15
pm
INSIGHTS INTO THE SPECIFICITY OF NEISSERIAL OPA
PROTEIN INTERACTIONS WITH HUMAN RECEPTORS.
Jennifer N. Martin
, Ryan H. Lo, Alison K. Criss, Linda Columbus
1011-P
lat
4:30
pm
AROMATIC RESIDUES DISPLAY AN ENERGETIC DEPTH-
DEPENDENCE IN LIPID BILAYERS THAT CAN BE MODULATED
BY NEAREST-NEIGHBOR INTERACTIONS.
Sarah K. McDonald
1012-P
lat
4:45
pm
PROTEIN AND ENVIRONMENTAL DETERMINANTS OF OMP
FATE IN LIPOSOMES.
Mark Culver
, Stephanos Gozali, Alison H.
Dewald
1013-P
lat
5:00
pm
STRUCTURE AND FUNCTION OF THE
β
-BARREL ASSEMBLY
MACHINE AND ITS ASSOCIATED CHAPERONES.
Marcelo C. Sousa
1014-P
lat
5:15
pm
UNFOLDING THE LUMINAL DOMAIN OF BTUB IN A NATIVE
BILAYER.
Curtis Balusek
, James C. Gumbart
1015-P
lat
5:30
pm
A SUBSET OF ANNULAR LIPIDS IS LINKED TO THE FLIPPASE
ACTIVITY OF AN ABC TRANSPORTER.
Cherine Bechara
, Anne
Noll, Nina Morgner, Matteo T. Degiacomi, Robert Tampe, Carol V.
Robinson
1016-P
lat
5:45
pm
“SNORKELING” OF THE CHARGED SIDECHAIN OF A
TRANSMEMBRANE PEPTIDE AS DIRECTLY OBSERVED BY
DOUBLE ELECTRON-ELECTRON RESONANCE EXPERIMENT.
Matthew Donohue, Maxim Voynov, Sergey Milikisiyants, Alex I. Smirnov,
Tatyana I. Smirnova
4:00
pm
–6:00
pm
, R
oom
307/308
Platform
Protein Structure and Conformation II
Co-Chairs
Lauren Porter, University of Maryland
Krishna Neupane, University of Alberta, Canada
1017-P
lat
4:00
pm
SOLUTION CONFORMATION OF THE UNBOUND
HIV-1 PROTEASE DERIVED FROM RESIDUAL DIPOLAR
COUPLINGS MEASURED AT AMBIENT AND HIGH-PRESSURE
CONDITIONS.
Julien Roche
, John M. Louis, Ad Bax
1018-P
lat
4:15
pm
UNDERSTANDING SIDE CHAIN CONFORMATIONAL
VARIABILITY IN PROTEINS.
Asmit Bhowmick
, Teresa Head-Gordon
1019-P
lat
4:30
pm
NAVIGATING IN THE PROTEIN UNIVERSE. Sergey
Nepomnyachiy, Rachel Kolodny,
Nir Ben-Tal
1020-P
lat
4:45
pm
PROTEIN EVOLUTION ACROSS FOLD CLASSES: A 3-
α
-HELIX
BUNDLE CAN SWITCH TO
β
,
α
/
β
, AND
α
+
β
FOLDS BY
STEPWISE MUTATION.
Lauren L. Porter
, Yanan He, Yihong Chen,
John Orban, Philip N. Bryan
1021-P
lat
5:00
pm
RESOLVING CONFORMATIONAL SWITCHING OF AAA
+
PROTEASE FTSH USING SINGLE-MOLECULE FRET.
Martine Ruer
, Philip Gröger, Nadine Bölke, Andreas Hartmann, Michael
Schlierf
1022-P
lat
5:15
pm
ANTI-PRION LIGAND BINDING PROMOTES NATIVE PRP
FOLDING OVER MISFOLDING AT THE SINGLE MOLECULE
LEVEL.
Krishna P. Neupane
, Amar Nath Gupta, Negar Rezajooei,
Michael T. Woodside
1023-P
lat
5:30
pm
WHAT COMPUTATIONAL METHODS CAN TEACH US ABOUT
THE ALZHEIMER-PROTECTIVE NATURE OF A2V- AND A2T-
MUTANT AMYLOID-BETA OLIGOMERS.
Jessica Nasica-Labouze
,
Bogdan Tarus, Phuong Nguyen, Philippe Derreumaux
1024-P
lat
5:45
pm
NMR STRUCTURE REVEALS NOVEL INTERACTIONS
BETWEEN INTRINSICALLY DISORDERED PEP-19 AND
CALMODULIN.
Xu Wang
, John A. Putkey
4:00
pm
–6:00
pm
, R
oom
309/310
Platform
Protein-Nucleic Acid Interactions II
Co-Chairs
Mark Williams, Northeastern University
Rifka Vlijm, Delft University of Technology, The Netherlands
1025-P
lat
4:00
pm
OLIGOMERIZATION KINETICS OF ORF1P IS CORRELATED
WITH LINE1 RETROTRANSPOSITION.
M. Nabuan Naufer
,
Anthony V. Furano, Mark C. Williams
1026-P
lat
4:15
pm
NUCLEOSOME ASSEMBLY DYNAMICS INVOLVE
SPONTANEOUS FLUCTUATIONS IN THE HANDEDNESS OF
TETRASOMES.
Rifka Vlijm
, Mina Lee, Orkide Ordu, Jan Lipfert,
Alexandra Lusser, Nynke Dekker, Cees Dekker
1027-P
lat
4:30
pm
FACILITATED DISSOCIATION OF PROTEIN FROM A SINGLE
DNA BINDING SITE.
Ramsey I. Kamar
, John F. Marko
1028-P
lat
4:45
pm
international
travel awardee
PROTEIN-DNA BINDING IN THE ABSENCE OF CONSENSUS
BINDING MOTIF.
Ariel Afek
, Joshua L. Schipper, Raluca Gordân,
David B. Lukatsky