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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
M
O
N
D
A
Y
960-P
lat
12:30
pm
INTERPRETATION OF SOLUTION X-RAY SCATTERING DATA
BY MOLECULAR DYNAMICS. Po-chia Chen, Levin Brinkmann,
Jochen S. Hub
10:45
am
–12:45
pm
, R
oom
307/308
Platform
Ligand-gated Channels
Co-Chairs
John Baenziger, University of Ottawa, Canada
Cynthia Czajkowski, University of Wisconsin-Madison
961-P
lat
10:45
am
DIVERGENT ROLES FOR M4 IN THE GATING OF TWO
PROKARYOTIC PENTAMERIC LIGAND-GATED ION
CHANNELS. Camille M. Henault, Peter F. Juranka, Julian S. Surujballi,
John E. Baenziger
962-P
lat
11:00
am
SINGLE MOLECULE MOTION MAP OF GLIC BY DIFFRACTED
X-RAY TRACKING.
Hiroshi Sekiguchi
, Yufuku Matsushita, Yuri
Nishino, Keigo Ikezaki, Atsuo Miyazawa, Naoto Yagi, Christele Huron,
Jean-Pierre Changeux, Pierre-Jean Corringer, Yuji C. Sasaki
963-P
lat
11:15
am
education
travel awardee
AN ELIC-GLIC CHIMERA REVEALS DISTINCT PATHWAYS OF
ACTIVATION IN THE CYS-LOOP FAMILY OF RECEPTORS.
Nicolaus Schmandt
, David T. Lodowski, Vivien Yee, Sudha Chakrapani
964-P
lat
11:30
am
education
travel awardee
DISULFIDE TRAPPING THE GABA-A RECEPTOR
EXTRACELLULAR BETA-5/BETA-5’ LOOP.
Cassandra M. Theusch
,
Cynthia Czajkowski
965-P
lat
11:45
am
CONFORMATIONAL DYNAMICS IN THE GABAA RECEPTOR.
Rilei Yu,
Philip C. Biggin
966-P
lat
12:00
pm
MONITORING THE WORK OF A SINGLE SUBUNIT IN
HOMOTETRAMERIC CNGA2 CHANNELS.
Klaus Benndorf
, Nisa
Wongsamitkul, Vasilica Nache, Thomas Eick, Sabine Hummert, Eckhard
Schulz, Ralf Schmauder, Jana Schirmeyer, Thomas Zimmer
967-P
lat
12:15
pm
ALLOSTERIC REGULATION OF THE CYCLIC NUCLEOTIDE-
BINDING DOMAIN IN HCN CHANNELS.
Hannah A. DeBerg
,
Shahidul M. Islam, Michael C. Puljung, Benoit Roux, William N.
Zagotta, Stefan Stoll
968-P
lat
12:30
pm
RAPID ACTIVATION OF DISTINCT CONDUCTING STATES IN
P2X RECEPTOR CHANNELS.
Mufeng Li
, Gilman Toombes, Shai D.
Silberberg, Kenton J. Swartz
10:45
am
–12:45
pm
, R
oom
309/310
Platform
Intrinsically Disordered Proteins (IDP)
Co-Chairs
Tharin Blumenschein, University of East Anglia, United Kingdom
Travis Hoppe, Drexel University
969-P
lat
10:45
am
A NEW AND UN-CONVENTIONAL ULTRAFAST BINDING
MECHANISM OF INTRINSICALLY DISORDERED PROTEINS
TO STRUCTURED PARTNERS.
Davide Mercadante
, Sigrid Milles,
Edward A. Lemke, Frauke Gräter
970-P
lat
11:00
am
COMBINATIONAL EVIDENCE THAT INTRINSIC DISORDER
PROVIDES BROAD ASSOCIATION PROFILES.
Travis A. Hoppe
,
Robert Best
971-P
lat
11:15
am
THE INTRINSICALLY DISORDERED C. TRACHOMATIS TARP
BINDS ACTIN WITH A PARTIALLY PREFORMED HELIX. James
L. Tolchard, Ted Hackstadt,
Tharin M. A. Blumenschein
972-P
lat
11:30
am
POST-TRANSLATIONAL MODIFICATION OF P27 REGULATES
SIGNAL TRANSMISSION VIA A DYNAMIC INTERACTION
WITH CDK2/CYCLIN.
Hugo Sanabria
, Maksym Tsytlonok, Yuefeng
Wang, Cheon-Gil Park, Suren Felekyan, Katherina Hemmen, Peter
Tompa, Claus A. M. Seidel
973-P
lat
11:45
am
EFFECTS OF CHARGE INTERACTIONS AND TRANSIENT
SECONDARY STRUCTURE ELEMENTS ON THE FUNCTION OF
THE DISORDERED RAM REGION OF THE NOTCH RECEPTOR.
Kathryn Sherry
, Rahul Das, Rohit Pappu, Doug Barrick
974-P
lat
12:00
pm
MOLECULAR SIMULATIONS OF UNFOLDED AND
INTRINSICALLY DISORDERED PROTEINS.
Gül H. Zerze
, Robert
B. Best, Jeetain Mittal
975-P
lat
12:15
pm
CONFORMATIONAL ENTROPIES OF UNFOLDED PEPTIDES:
THE SOURCE OF A REALISTIC ESTIMATION OF THE
ENTROPY OF UNFOLDED PEPTIDES AND PROTEINS.
Reinhard Schweitzer-Stenner
, Siobhan E. Toal
976-P
lat
12:30
pm
EVIDENCE FOR INTERNAL FRICTION IN IDPS OF THE
CALCITONIN PEPTIDE FAMILY. Sara M. Sizemore, Stephanie M.
Cope,
Sara M. Vaiana
10:45
am
–12:45
pm
, R
oom
314/315
Platform
Cardiac, Smooth, and Skeletal Muscle
Electrophysiology
Co-Chairs
Cathy Proenza, University of Colorado, Denver
Eleonora Grandi, University of California, Davis
977-P
lat
10:45
am
IONIC MECHANISMS THAT UNDERLIE VENTRICULAR
ACTION POTENTIAL PROLONGATION FOLLOWING LOSS OF
CAVEOLIN-3 IN ADULT TRANSGENIC MICE.
Vignesh Ramchandran
, Thomas O’Hara, Yogananda S. Markandeya,
Ravi C. Balijepalli, Timothy J. Kamp, Natalia A. Trayanova
978-P
lat
11:00
am
DIABETES SLOWS HEART RATE VIA ELECTRICAL
REMODELING OF K
+
CURRENTS IN SINOATRIAL NODE
MYOCYTES. Joshua R. St. Clair, Emily J. Sharpe, Andrew Hagar,
Clayton Garthe, Julie Juchno,
Cathy Proenza
979-P
lat
11:15
am
CARDIAC SPECIFIC LEUCINE-RICH REPEAT CONTAINING 10
(LRRC10) PROTEIN INTERACTS WITH AND REGULATES THE
CAV1.2 L-TYPE CA2+ CHANNELS.
Marites T. Woon
, Adrian C.
Grimes, Courtney R. Reynolds, Matthew J. Brody, Youngsook Lee, Ravi
C. Balijepalli