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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
980-P
lat
11:30
am
THE CA
2+
CLOCK IS NOT GOVERNED BY A SINGLE CAMKII
OR PKA PHOSPHORYLATION SITE FOR FIGHT OR FLIGHT
RESPONSES.
Yuejin Wu
, William J. Kutschke, Hector H. Valdivia,
Xander H.T. Wehrens, Mark E. Anderson
981-P
lat
11:45
am
RANOLAZINE PREVENTS PHASE-3 EARLY
AFTERDEPOLARIZATIONS IN HUMAN ATRIAL MYOCYTES
BY INHIBITING NA CURRENT NON-EQUILIBRIUM
REACTIVATION. Stefano Morotti, Andrew D. McCulloch, Donald M.
Bers, Andrew G. Edwards,
Eleonora Grandi
982-P
lat
12:00
pm
PROBING THE TRAFFICKING ROUTES OF KCNQ1 AND KCNE1
AFTER THEIR ER EXIT. Min Jiang, Mei Zhang, Scott C. Henderson,
Tseng Gea-Ny
983-P
lat
12:15
pm
TRAFFICKING AND GATING MECHANISMS OF HERG1A
C-TERMINUS (LQTS-2) TRUNCATION MUTATIONS ON
HERG1A-HERG1B HETERO-MULTIMERIC CHANNEL. Akil
Puckerin, Donald D. Chang, Prakash Subramanyam, Henry M. Colecraft,
Ademuyiwa S. Aromolaran
984-P
lat
12:30
pm
DOMINANT NEGATIVE CONSEQUENCES OF A HERG 1B
MUTATION ASSOCIATED WITH INTRAUTERINE FETAL
DEATH.
David K. Jones
, Sunita Joshi, Fang Liu, Gail A. Robertson
10:45
am
–12:45
pm
, R
oom
316/317
Platform
Membrane Pumps, Transporters, and
Exchangers II
Co-Chairs
Vanessa Leone, NIH
Eduardo Chufan, NIH
985-P
lat
10:45
am
ON THE NA
+
/H
+
SELECTIVITY OF MEMBRANE TRANSPORTERS
AND ENZYMES: EXPERIMENTAL AND THEORETICAL STUDIES
OF AN ATP-SYNTHASE ROTOR RING.
Vanessa Leone
, Ernst Grell,
Denys Pogoryelov, Thomas Meier, José D. Faraldo-Gómez
986-P
lat
11:00
am
education
travel awardee
RECENT STRUCTURES AND MOLECULAR DYNAMICS
SIMULATIONS OFFER NEW PERSPECTIVE ON NA
+
/H
+
ANTIPORTERS.
David L. Dotson
, Chiara Lee, Shoko Yashiro,
Povilas Uzdavinys, Christoph von Ballmoos, David Drew, Alexander D.
Cameron, Oliver Beckstein
987-P
lat
11:15
am
education
travel awardee
UNDERSTANDING SELECTIVITY OF THE NA
+
/K
+
-ATPASE
USING A COMPUTATIONAL APPROACH.
Asghar M. Razavi
,
Vincenzo Carnevale, Lucie Delemotte, Vincent A. Voelz
988-P
lat
11:30
am
X-RAY CRYSTALLOGRAPHIC STUDY OF NA,K-ATPASE IN
COMPLEX WITH CARDIOTONIC STEROIDS.
Haruo Ogawa
,
Kanna Motoyama, Flemming Cornelius, Bente Vilsen, Chikashi
Toyoshima
989-P
lat
11:45
am
IDENTIFICATION OF STRUCTURAL MOTIFS IN
P-GLYCOPROTEIN RESPONSIBLE FOR THE DRUG-MEDIATED
INHIBITION OF ATP HYDROLYSIS.
Eduardo E. Chufan
, Khyati
Kapoor, Suresh V. Ambudkar
990-P
lat
12:00
pm
education
travel awardee
THE HYDROLYSIS CYCLE OF ATP-BINDING CASSETTE
NUCLEOTIDE-BINDING DOMAINS.
Srinivasan Krishnan
, Maria
E. Zoghbi, Guillermo A. Altenberg
991-P
lat
12:15
pm
RECONSTITUTION OF HUMAN ABC TRANSPORTER
MRP3 INTO GIANT UNILAMELLAR VESICLES FOR SINGLE
MOLECULE TRANSPORT RECORDINGS ON MICRO-
STRUCTURED BIOCHIPS.
Patrick Seelheim
, Adriane Wüllner, Hans-
Joachim Galla
992-P
lat
12:30
pm
MOLECULAR DYNAMICS SIMULATION STUDY OF A MUTANT
CONSTRUCT OF THE ARCHAEAL GLUTAMATE TRANSPORTER
GLTPH WITH TRANSPORT RATES AS FAST AS ITS HUMAN
COUNTERPART.
Michel A. Cuendet
, Sebastian Stolzenberg, George
Khelashvili, Harel Weinstein
11:30
am
–12:30
pm
, R
oom
301/302/303
Career Center Workshop
Career Planning and Job Searching for
Science Professionals:
Academic Opportunities
Learn how to create a flexible career plan for yourself, and identify and
leverage your skills, expertise and experience to find a career (not just
a job) that is right for you. Special emphasis will be placed on tips for
finding and launching a career in academia, but we will also incorporate
the development of a contingency plan for the unexpected twists and
turns in life.
11:30
am
–1:00
pm
, H
all
C, R
oom
A
Exhibitor Presentation
Asylum Research, an Oxford Instruments
Company
There’s No Other AFM Like Cypher™ – High Resolution Atomic Force
Microscopy Made Easier and Faster
Asylum Research has focused on improving AFM instrumentation to
make imaging in liquid easier, faster and more quantitative for life science
applications. Please join us for this ‘Lunch and Learn’ presentation that
will focus on the latest technical advances in AFM that enable high
resolution imaging of the structure and dynamics of samples including
proteins, lipids and nucleic acids. We’ll show examples of how the Cypher
ES Environmental AFM allows users to control the environment around
their sample and perform perfusion experiments easily. You’ll learn about
Cypher’s numerous ease-of-use features such as GetStarted™, GetReal™,
and blueDrive™ for easy and stable imaging in liquid. We will introduce
you to Fast Force Mapping, our unique technology that measures
mechanical properties of your samples faster and more reliably. This is also
a great opportunity to ask our scientists any questions you may have about
AFM.
Presenter
Irène Revenko, Applications Scientist, Asylum Research, an Oxford
Instruments Company