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S784

ESTRO 36 2017

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pass-rates obtained for clinical plans DQA were

comparable to film pass-rates. The possibility to use the

beam nominal position was validated and can be an

alternative to eliminate SDD and angle dependence.

EP-1484 Validation of ptw’s diamond as alternative

method for the imrt-vmat pretreatment verification

A. Niebla Piñero

1

, B.C. Portas Ferradás

1

, P. Rosa

Menéndez

1

, J.A. Merino Gestoso

1

, M. Rodríguez Pazos

1

, D.

Pardo Calvo

1

, B. Sobral Aspérez

1

1

Hospital Universitario Nuestra Señora de Candelaria,

Medical Physics, Santa Cruz de Tenerife, Spain

Purpose or Objective

The aim of the study is the validation of the software

DIAMOND, as alternative method to ion chamber point

dose measurements to verify prostate’s IMRT-VMAT plans.

For this purpose, we have selected 109 IMRT and 65 VMAT

treated plans between the 12/09/2013 to 08/16/2016. We

have compared the results using Diamond with the ion

chamber results in the pretreatment verification. Using a

ROC analysis we have obtained the new tolerances to

apply in our QA program.

Material and Methods

We have selected 109 IMRT step & shoot plans calculated

with CMS XiO and 65 VMAT calculated with CMS MONACO.

This plans were calculated over the own patient’s CT and

also over the I’mRT phantom’s CT used for the point dose

verification. These plans were sent to DIAMOND to make

the recalculation in two points: One of them in a high

dose-low gradient region (P1), and the other in a high

dose-high gradient region (P2). In our QA program for ion

chamber verification, we have established a 3% of

deviation in P1 points, and 5% deviation in P2 points.

Results

We have recalculated the dose using DIAMOND in P1 and

P2 points over the definitive patient plan, and also over

the definitive plan simulated in the phantom. The results

were compared with the TPS values. Furthermore, we

have compared this deviation with the deviation between

the measurements and the dose calculated in the TPS. The

following table shows some results:

To establish new tolerances, we have looked into the 95%

confidence intervals for dose deviation, and also we have

done a ROC analysis between the new method (DIAMOND)

and the old (ion chamber). Even though, we show in our

results that 95% confidence intervals are asymmetric, we

have chosen our tolerances in a symmetric interval. We

believe that this decision will make the analysis more clear

and will avoid errors in the future.

As we show in figure 1, differences may appear between

phantom and patient results for P2 points in VMAT plans.

These differences could be associated with differents

algorithms used in the TPS (Monte Carlo) and the Diamond

(Clarkson), and their differences in a heterogeneity

medium. Although differences exist, we can correlate the

results between the new and the old method, over the

phantom’s plan and also over the patient’s plan. Even

though, we have obtained good results in the global plan

analysis, we have seen that it’s possible to obtain big

differences in a field. This can be explained because the

calculated point may be in a penumbra region, where the

uncertainties in the calculation are bigger than the

established tolerances.

Conclusion

We have checked the DIAMOND’s viability to verify IMRT-

VMAT plans, also we have calculated tolerances to apply

in clinical use. With this new method, we will decrease

the time in the verification and also decrease the time

between the moment that the plan is calculated and the

beginning of the treatment.

EP-1485 Dosimetric characterization of an high

definition MLC for stereotactic radiotherapy

treatments.

F. Rosica

1

, F. Bartolucci

1

, C. Fidanza

1

, A. Savini

1

, D.

Ciuffetelli

1

, A. Rastelli

1

, G. Orlandi

1

1

USL di Teramo Azienda ASL 4, Medical Physics, Teramo

TE, Italy

Purpose or Objective

High definition multi leaf collimators (MLCs) with reduced

leaf width are beneficial for treating small lesions in

modern stereotactic radiotherapy. In general, leaves have

special design details that may have a strong impact on

the delivered dose. The aim of this study was to

characterize the dosimetric impact of such details in the

Varian HD120 MLC for several beam qualities including

flattening-filter-free (FFF) modalities.

Material and Methods

A set of MLC-collimated fields was irradiated using a

Varian TrueBeam STx linear accelerator equipped with the

HD120 MLC (beam qualities: 6MV, 10MV, 6MV-FFF, 10MV-

FFF). These fields were designed using several abutment

configurations (e.g. picket fence) in order to enhance the

dosimetric impact of the MLC design details such as

tongue-and-groove and rounded leaf tip. Dose profile

scans were measured in a motorized water phantom using

small detectors (IBA-Razor stereotactic diode and PTW-

microDiamond 60019). Dose profiles of the abutted fields

were summed and compared with the dose profiles of the

corresponding open fields. In addition, average MLC

transmission was measured using a Farmer ion chamber

(IBA-FC 65-G).

Results