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S783

ESTRO 36 2017

_______________________________________________________________________________________________

The calculation models the spatial response of the IQM

chamber and the fluence transmitted through the

individual collimating elements. The chamber response is

modelled as a 2D map. The fluence from the machine is

divided into 2 components: a point source at the target

and an extended source at the flattening filter, referred

to as the primary and extended source, respectively. The

primary source is characterized by a radial intensity

profile and is attenuated through the jaws and multileaf

collimator. Transmission is calculated for a 2D array

matching the chamber response map, and area averaged

fluence is calculated for moving collimating elements

during beam delivery. The extended source is modeled as

a Gaussian distributed source with a Compton angular

intensity distribution. The contribution of the Gaussian

source to each element in the fluence array is raytraced

through the collimation to obtain the area averaged

fluence. An element-wise multiplication of the chamber

response map with the primary and extended source

fluence is summed to generate the predicted signal,

modified by factors reflecting the chamber volume, the

intensity of the primary and extended sources and change

in machine output with field aperture. The model has

been implemented for Varian and Elekta treatment units,

with calculations and measurements compared for

clinically relevant fields.

Results

Parameters for the model were determined from a series

of rectangular field measurements with the IQM chamber

combined with ion chamber measurements. Iterative

optimization of parameter values to match rectangular

field IQM measurement were performed. Similar

techniques were used to extract normalization

parameters.

The agreement between the calculated and measured

signals on a Varian TrueBeam unit for over 300 different

IMRT field segments from Prostate and Head & Neck plans

show 99% of segments agree within ±5%; 95% within ±3%.

Similar results were seen for an Elekta Agility unit in a

sample of over 400 different IMRT field segments, with

97% of segments agreeing within ±5% and 91% within

±3%.

Conclusion

A 2-source calculation model has been implemented for an

area-fluence monitor designed for on-line patient QA.

EP-1483 Pre-Treatment QA of MLC plans on a

CyberKnife M6 using a liquid ion chamber array.

L. Masi

1

, R. Doro

1

, O. Blanck

2

, S. Calusi

3

, I. Bonucci

4

, S.

Cipressi

4

, V. Di Cataldo

4

, L. Livi

5

1

IFCA, Medical Physics, Firenze, Italy

2

Saphir Radiosurgery Center, Medical Physics, Frankfurt/

Gustrow, Germany

3

University of Florence, Department of Clinical and

Experimental Biomedical Sciences "Mario Serio", Firenze,

Italy

4

IFCA, Radiation Oncology, Firenze, Italy

5

Azienda Ospedaliera Universitaria Careggi,

Radiotherapy Unit, Firenze, Italy

Purpose or Objective

CyberKnife MLC plans require accurate patient-specific

QA. The purpose of this study is to validate the use of a

liquid ion chamber array for Delivery Quality Assurance

(DQA) of robotic MLC plans, using several test scenarios

and routine patient plans and comparing results to film

dosimetry.

Material and Methods

Five preliminary sensitivity test scenarios were created

from a baseline plan modifying each MLC segment by

introducing increasing shifts in leaves positions (0.5 mm -

2 mm). The baseline and test plans were delivered to an

Octavius 1000SRS array (PTW) as well as to EBT3 films. An

average correction was applied to 1000SRS results to

account for the response dependence on source-detector-

distance (SDD) [O. Blanck

et.al

. Phys Med 2016]. The same

five test plans were delivered a second time to the

1000SRS re-orienting all beams perpendicularly to the

array (nominal position) to eliminate SDD and angle

dependence. As a second step 40 clinical MLC plans

optimized for various treatment sites (liver, spine,

prostate) were delivered to the liquid ion chamber array

for patient-specific QA using both the clinical beam

orientations and the beam “nominal position”. For the

latter only a subset of segments(18-21) was selected.

Finally, for 15 out of 40 clinical plans a film-based DQA

was also performed. All results were analyzed using (2%,

2mm),( 3%, 1mm) and (2%, 1mm) gamma index criteria [O.

Blanck

et.al.

Phys Med 2016].

Results

The pass-rate reductions from the baseline,obtained

delivering the five test plans, are shown in fig.1 for (3%,

1mm) gamma criteria. The Octavius 1000SRS showed a

good sensitivity to simulated delivery errors with pass-rate

reductions increasing from 1.7% to a maximum of 43% with

increasing leaves shifts (0.5 mm - 2 mm). Similar

sensitivity was observed when the beams were re-oriented

in the nominal position geometry. The pass-rate

reductions observed with films showed a more irregular

trend, and the maximum reduction was 16%. The average

pass-rates obtained over clinical plans are shown in fig.2,

for the three gamma index criteria. The mean values

obtained by the 1000 SRS array, using both the clinical and

nominal beam geometry, and by film-dosimetry are all

above 92%, when using 3%, 1mm criteria. Differences

among the mean pass-rates observed for the three

measurement modalities were not statistically significant

(p> 0.1, t-test)

Conclusion

The results confirm that the 1000SRS array is reliable for

pre-treatment QA of CyberKnife MLC plans. The test

scenarios highlighted a higher sensitivity to small leaves

shifts than what observed by film dosimetry. The gamma