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4
Evidence-based management of T1N0
glottic carcinomas:
level 3
0
0.2
0.4
0.6
0.8
1
0 2 4 6 8 10 12 14 16
Open Surgery
Radiotherapy
Laser
Probability of loco-regional
control
Time from diagnosis (years)
p = n.s.
34
42
31
20
20
5
2
3
0
Rosier,
R&O
, 1998
EHNS-ESTRO H&N course
Florence, June 2016
Radiotherapy in early stage glottic
cancers:
level 3
T
2
Carcinoma of the Glottis : Local Control with
Radiotherapy and Surgical Salvage
Reference
Patients (
n
)
Initial Local Control
Ultimate Local Control
Elman et al (1979)
64
T
2a
, 146
T
2a
, 80%
T
2a
, 96%
T
2b
, 82
T
2b
, 72%
T
2b
, 96%
Fletcher and Hamberger (1974)
65
175
74%
94%
Mittal at al (1983)
66
327
69%
___
Howell-Burke at al (1985)
67
114
68%
76%
Amornmarn et al (1985)
67
34
88%
94%
Karim et al (1987)
76
156
81%
95%
Wang (1990)
71
173
69%
86%
Le (1997)
71
83
67%
___
Mendenhall et al (2001)
72
120
75%
95%
Frata et al (2005)
77
256
70%
85%
EHNS-ESTRO H&N course
Florence, June 2016