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A high throughput quantitative and
confirmatory method for the analysis of
monofluoracetate in nutritional products
by liquid chromatography-mass
spectrometry
Nick Cellar Stefan Ehling and Murali Reddy
Proprietaryand confidential — do not distribute
© 2015 Abbott Laboratories
,
,
March, 2015
MONOFLUOROACETATE SODIUM
•
Molecular Formula: C
2
H
2
FNaO
2
Average mass: 100.024 Da
•
Sodium fluoroacetate is a fluffy white material at room
temperature, which forms colorless solutions with water and is
normally odorless.
•
Used to control wild dogs, feral pigs, foxes, cats, possums and
rabbits in New Zealand and Australia
•
Occurs naturally in a number of native plant species including
Acacia georginae (Georgina gidgee) and members of the
Gastrolobium and Oxylobium genera.
Proprietaryand confidential — do not distribute
© 2015 Abbott Laboratories
•
Fluoroacetate interferes with the citric acid (Krebs) cycle. Known
toxicity to carnivores (dogs)/herbivores (cattle)/omnivores (pigs)
•
The LD50 value for cattle is 0.4 mg/Kg body weight
March17,2015
MFA‐AOAC,2015
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