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TRG : WHICH IS BEST ?

Trakarnsarga et al ( 2014 )

563 rectal cancers : cT3/4 or N+ : 1998 – 2007

CRT : 50.4 Gy plus 5FU based chemotherapy

TME after 6 – 8 weeks

Median F.U. 39 months

pCR = 21 % ; LR = 2 %; DM = 17 %

TRG determined by expert GI pathologists

Mandard ( 5 & 3 tier )

Dworak / Rodel ( 5 & 3 tier )

MSKCC

AJCC / CAP