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Venous Invasion after CRT

No.

%V1/2 10yr LR 10yr

DM

10 yr

DFS

3 yr DFS

Fokas et al

2014

CAO/ARO/A10-94

V0

386 4.7% 6.3% 28% 74.5%

V1/V2

9.1% 57.9%* 42.9%*

Chand et al

2015

V0

188 19%

65.9%

V1/V2

36.9%**

pEMVI is still a strong prognostic factor for DFS & the development

of distant metastasis after pre-operative chemoradiotherapy !!

( * p < 0.002 )