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Pathological stage and survival after pre-

Operative Chemoradiotherapy for rectal

cancer

• CRM positive in 4 %

• LR rate : 3 % ; distant metastases : 20 %.

• 5 yr disease free survival : 74 %

• Best predictor of DFS was pathological stage :

concordance index*

Pre-treatment clinical stage

0.5

Pathological stage

0.75

% tumour response

0.65

*

ability to predict disease recurrence

Quah et al 2008