Pathological stage and survival after pre-
Operative Chemoradiotherapy for rectal
cancer
• CRM positive in 4 %
• LR rate : 3 % ; distant metastases : 20 %.
• 5 yr disease free survival : 74 %
• Best predictor of DFS was pathological stage :
concordance index*
Pre-treatment clinical stage
0.5
Pathological stage
0.75
% tumour response
0.65
*
ability to predict disease recurrence
Quah et al 2008