454 / 1068
TRG : local recurrence & survival
No.
5 yr LR 5 yr distant
metastasis
4 yr DFS
TRG 0
22
5 % 9 %
91 %*
131 cT3/T4 rectal cancers resected after pre-op CRT ( polish trial )
median follow-up 4 years
TRG 1
40
9 % 34 % 67 %
TRG 2
40
16 % 35 % 54 %
TRG 3
29
26 % 47 % 47 %
NO significant difference in LR, distant recurrence or 4 yr
disease free survival between TRG 1, 2 and 3 !!!
( * P = 0.015 )
( Bujko et al 2010 )