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Pelvic OARs constraints: bone marrow
- Acute Hematological toxicity reported in
RT+CHT for rectal ca; unclear the long-term
impact
- Evidence of dose-volume effects for the
pelvic bone marrow in rectal and anal canal
ca. with 3DCRT +CHT (Mell 2007)
- Predictive models of hematological tox for
rectal ca treated with 3DCRT/IMRT +CHT
(Yang 2014, Wan 2015)
- Not yet reported BM-sparing planning
strategies for rectal cancer…..potential
interplay with bowel/bladder sparing
Yang 2014