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- At our Institute 2007-2009: pilot study exploring moderate hypo-
fractionation, 41.4 Gy/18 fractions + Oxa/5FU*
- Daily image-guided Tomotherapy
- Feasible and efficient : G3 GI: 9%, pCR:28 % (data of first 35 pts)
- Introducing MRI for planning (+ diffusion MRI since 2013)
Adaptive RT: background II
*
Oxaliplatin 100mg/m2 on day -14, 0 (start of RT), +14; 5-FU 250mg/m2/day c.i. from day -14 to the end of RT.