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Question 2: Which study-arm is biologically the most iso-

effective with the standard-arm (74 Gy), regarding tumour

control?

Calculation:

E/α = BED = D (1 +

)

- 74 Gy – arm

= 74 (1 +

) = 172,67 Gy

- 60 Gy – arm

= 60 (1 +

) = 180 Gy

- 57 Gy – arm

= 57 (1 +

) = 171 Gy

Prostate cancer case