1364-1365 / 2063
How to manage uncertainties?
35x 2.2 Gy
5x 7 Gy
Incorporate uncertainties
into treatment planning
Adapt plan in real-time to
occurring events
Geometrical margins derived
from population based statistics
Van Herk et al., (2000), IJROBP
Optimize worst case scenario
by simulating uncertainties as
dosimetric perturbations
Inherent plan robustness
Real-time organ
motion monitoring
Real-time adaptation of
treatment plan to actual position
Real-time adaptation
Optimum?
‘Anticipate to what you expect’
‘Act to what you see’
‘Act when necessary, anticipate as
far as necessary’