Introduction
•
Changes in normal tissue tolerance with time
Isoeffective dose (Gy)
Time interval (days)
recovery kinetics
repopulation long-term
restoration
spinal cord
oral mucosa
160
140
120
100
80
60
40
20
0
0.00001 0.0001 0.001 0.01 0.1
1
10
100
Long-term recovery
from radiation injury
in some tissues
(not all!)